Ehlers danlos syndrome
Types of Ehlers Danlos syndrome
There are six major types of EDS. All types affect the joints and most affect the skin.\
- the most common type
- caused by mutations in two different genes
- formerly called type III
- Classical types I & II
Vascular (type IV)
- most severe type
- life expectancy is 48 years
Kyphoscoliosis (type VI)
fewer than 60 cases reported worldwide
- fewer than 60 cases reported worldwide
Arthrochalasis types (VIIA & B)
- about 30 cases reported worldwide
Dermatosparaxis type (VIIC)
- the most rare of all six types, with only 10 cases reported worldwide
What causes Ehlers Danlos syndrome?
If you child has Ehlers Danlos syndrome, she has inherited at least one copy of an altered gene. Some types of the disorder result from a genetic defect that disrupts the baby's body's ability to make collagen, a primary component of connective tissue. This causes the child to have joint pain and other symptoms of the disorder.
What are the symptoms of Ehlers Danlos syndrome?
The symptoms of EDS vary depending on the type of disorder, and can range from mild to life threatening. Some of the common symptoms include:
- hypermobility in the hands, fingers and toes
- loose joints that are prone to sprains, dislocations and double-jointedness
- flat feet
- a high narrow palate with dental crowding
- pale, smooth skin that bruises easily
- skin that stretches easily
- wounds that don't heal easily and with abnormal scarring
- myalgia and arthralgia
- muscle weakness, especially when cold
- early onset osteoarthritis
Some of the less common symptoms include:
- low bone density
- irritable bowel syndrome
- carpal tunnel syndrome
- hearing loss
- delayed motor skills in infants
- large eyes, small chin, thin nose and lips
- small stature
What are the complications?
People with EDS, especially the kyphoscoliosis type, are more prone to osteoporosis and eye problems. Other types may increase the risk of developing gum disease and mitral valve prolapse, a heart condition in which one of the valves in the heart does not close properly, which affects the flow of blood and the delivery of oxygen to throughout the child's body.
Can a child with EDS be physically active?
Children with EDS are encouraged to do non-weight bearing activities, such as swimming, which does not tax the joints. Repetitive activities, like weight lifting, are discouraged. Push-ups and other exercises that require pushing with the palm of the hand can cause fingers to hyper-extend and are therefore not recommended.