Pulmonary vein stenosis
Research & Innovation
At Children’s Hospital Boston, our care is informed by our research, and our discoveries in the laboratory strengthen the care we provide at each child's bedside. Children’s scientific research program is one of the largest and most active of any pediatric hospital in the world.
In particular, our cardiovascular and cardiac surgery researchers are yielding crucial insights into the causes and development of heart defects and disorders; paving ground for the most promising new treatments and interventions; and offering ideas and discoveries that could lead to cures.
Learn more about our ongoing research efforts.
Among our current research projects with promise for treating pulmonary vein stenosis is an exciting study:
Treating pulmonary vein stenosis by targeting abnormal cell growth
Children’s and the Dana-Farber Cancer Institute are conducting a research study in patients who have multi-vessel (occurring in at least two blood vessels), intraluminal (affecting the lumen, or openings into the blood vessels) pulmonary vein stenosis. They aim to determine whether two drugs that target certain tumors may also be effective in controlling the abnormal cell growth that characterizes this type of pulmonary vein stenosis.
|Children's in action|
|Watch some of our commonly used cardiac procedures.|
|Did you know?|
|Children's helps adults with congenital heart problems, too.|
Children’s is known for pioneering some of the most effective diagnostic tools, therapies and preventive approaches in pediatric cardiology. A significant part of our success comes from our commitment to research—and to advancing the frontiers of mental health care by conducting clinical trials.
Children’s coordinates hundreds of clinical trials at any given time. Clinical trials are studies that may involve:
- evaluating the effectiveness of a new drug therapy
- testing a new diagnostic procedure or device
- examining a new treatment method for a particular condition
- taking a closer look at the causes and progression of specific diseases
Children’s is involved in several multi-site clinical trials and studies focusing on pediatric cardiology and cardiac surgery, in particular. While children must meet strict criteria in order to be eligible for a clinical trial, your child may be eligible to take part in a study. Before considering this option, you should be sure to:
- consult with your child’s treating physician and treatment team
- gather as much information as possible about the specific course of action outlined in the trial
- do your own research about the latest breakthroughs relating to your child’s condition
If your physician recommends that your child participate in a clinical trial, you can feel confident that the plan detailed for that study represents the best and most innovative care available. Taking part in a clinical trial at Children’s is entirely voluntary. Our team will be sure to fully address any questions you may have, and you may remove your child from the medical study at any time.
- Search current and upcoming clinical trials at Children’s
- Search the National Institutes of Health’s list of clinical trials taking place around the world
|The role of stem cells in the fight against heart disease|
|Learn more about our research in this vital area.|
|Follow Children’s long history of innovation in pediatric heart care|
|In 1938, Children’s cardiac surgeon Robert Gross, MD, performed the world’s first successful surgery to correct a child’s heart defect. Since that time, Children’s has gained recognition around the globe for our leadership in pediatric cardiology, and we continue to make critical advances in the field. Follow our timeline of Children’s innovations in heart care.|