Research & Innovation
Children’s Hospital Boston’s ophthalmologists are actively involved in research that is shaping the way disorders like Duane syndrome are detected and treated in patients around the world. At the same time, our doctors are also training fellows and residents—preparing the next generation of pediatric eye specialists.
Here are just a few of our current research projects:
Tracing the genetics behind Duane syndrome with radial ray anomalies
One type of inherited Duane syndrome that is associated with other birth defects is Duane syndrome with radial ray anomalies. Children’s neurology researcher Elizabeth Engle, MD, and members of her laboratory have described the mapping of this disorder to Chromosome 20 and identification of the gene, SALL4, as being causative for the disorder.. Learn more.
Understanding the genetics of misaligned eyes
Children’s has initiated a very large, ongoing study to determine the genetic basis for childhood strabismus. Because adult strabismus is often a condition that carries over from childhood, this research is highly pertinent to sufferers of adult strabismus, as well as childhood strabismus.
Pioneering new eye surgery techniques
Children’s is at the forefront of developing new surgery techniques. One particular area of study is how sophisticated imagery—namely how high resolution MRI (magnetic resonance imaging)—can be used to better reveal the orbit of the eye. Such high-resolution imagery enables our surgeons to be much more precise with preoperative planning. Learn more about advances in MRI technology at Children’s.
Learn more about ophthalmology research at Children’s.
Children’s is known for pioneering some of the most effective diagnostic tools, therapies and preventive approaches in pediatric medicine. A significant part of our success comes from our commitment to research—and to advancing the frontiers of mental health care by conducting clinical trials.
Children’s coordinates hundreds of clinical trials at any given time. Clinical trials are studies that may involve:
- evaluating the effectiveness of a new drug therapy
- testing a new diagnostic procedure or device
- examining a new treatment method for a particular condition
- taking a closer look at the causes and progression of specific diseases
While children must meet strict criteria in order to be eligible for a clinical trial, your child may be eligible to take part in a study. Before considering this option, you should be sure to:
- consult with your child’s treating physician and treatment team
- gather as much information as possible about the specific course of action outlined in the trial
- do your own research about the latest breakthroughs relating to your child’s condition
If your physician recommends that your child participate in a clinical trial, you can feel confident that the plan detailed for that study represents the best and most innovative care available. Taking part in a clinical trial at Children’s is entirely voluntary. Our team will be sure to fully address any questions you may have, and you may remove your child from the medical study at any time.
- Search current and upcoming clinical trials at Children’s
- Search the National Institutes of Health’s list of clinical trials taking place around the world
|Current research projects in Ophthalmology|
Check out some of our researchers’ latest work.