Research Faculty

Laurie Cohen, MD

Department Endocrinology
Hospital Title Director, Neuroendocrinology Program
Academic Title Assistant Professor of Pediatrics
Phone 617-355-7476
Fax 617-730-0194
Email Laurie Cohen
Location 300 Longwood Avenue
Boston MA 02115

Research Overview

Laurie Cohen's research in basic science focuses on determining the pathogenesis of hypopituitarism in children with short stature and in characterizing growth hormone gene regulation. Her laboratory interests have dovetailed with her clinical work in treating hypopituitarism as a side effect of treatment for cancer, especially brain tumors. Her current goal is to characterize endocrine sequelae in patients with hematologic and oncologic disorders.

In other endocrine research, she is investigating growth and insulin resistance in neuroblastoma survivors and the mechanisms of hypothalamic obesity.

About Laurie Cohen

Laurie Cohen received her MD from Cornell University College of Medicine. She completed an internship and residency at Yale-New Haven Hospital and a fellowship at Children's Hospital Boston.

She is the recipient of the Priscilla and Richard Hunt Fellowship, Harvard Medical School 50th Anniversary Program for Scholars in Medicine.

Key Publications

  • Cohen LE, Zanger K, Brue T, Wondisford FE, Radovick S. Defective retinoic acid regulation of the Pit-1 gene enhancer: a novel mechanism of combined pituitary hormone deficiency. Molecular Endocrinology 1999; 13: 476-484.
  • Cohen LE, Hashimoto Y, Zanger K, Wondisford FE, Radovick S. CREB-independent regulation by CBP: a novel mechanism of human growth hormone gene expression. Journal of Clinical Investigation 1999; 104: 1123.
  • Dalton VK, Rue M, Silverman LB, Gelber RD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Tarbell NJ, Sallan SE, Cohen LE. Height and weight in children treated for acute lymphoblastic leukemia: relationship to central nervous system treatment. Journal of Clinical Oncology 2003; 21: 2953-2060.