Research Faculty

Leonard Rappaport, MD

Department Developmental Medicine
Hospital Title Chief,
Division of Developmental Medicine
Director,
Developmental Medicine Center
Academic Title Professor
Phone 617-355-7030
Fax 617-730-0252
Email Leonard Rappaport
Location 300 Longwood Avenue
Fegan-10
Boston MA 02115

Research Overview

One goal of Leonard Rappaport's work is to gain a better understanding of the effects of medical and surgical interventions on development and neurological status later in childhood. He seeks to use that information to improve developmental and behavioral outcome after infant cardiac surgery.

His lab is also collaborating with Children's Genomics Center and MIT's Department of Brain and Cognitive Sciences to better understand the etiology of developmental disorders. One of the goals of this work is to improve the methods of diagnosing and treating autism spectrum disorders.

Rappaport and colleagues are also investigating the etiology and treatment of elimination disorders such as encopresis and enuresis.

About Leonard Rappaport

Leonard Rappaport received his MD from Yale University School of Medicine. He completed an internship, residency, and fellowship at Childrens Hospital Boston.

Dr. Rappaport serves on the Executive Board for NIH-NHLBI trials in infant heart surgery.

Key Publications

  • Bellinger D, Jonas R, Rappaport L, Wypij D, Wernovsky G, Kuban K, Barnes P, Holmes G, Hickey P, Strand R, Walsh A, Helmers S, Constantinou J, Carrazana E, Mayer J, Hanley F, Casteneda A, Ware J, Newburger JA. Comparison of the developmental and neurologic status at one year of children who underwent heart surgery using hypothermic circulatory arrest or low-flow cardiopulmonary bypass. New England Journal of Medicine 1995; 332: 549-555.
     
  • Rappaport LD, Wypij D, Jonas R, Bellinger DB, Helmers P, Newburger J. Relation of seizures following cardiac surgery in early infancy to neurodevelopmental outcome. Circulation 1998; 97: 773-779.
     
  • Landgraf J, Rich M, Rappaport LA. Measuring quality of life in children with ADHD and their families. Archives of Child and Adolescent Pediatrics 2001; 156: 384-391.