Research Faculty

Heung Bae Kim, MD

Department General Surgery
Hospital Title Director, Pediatric Transplant Center
Academic Title Assistant Professor of Surgery, Harvard Medical School
Phone 617-355-7800
Fax 617-730-0475
Email Heung Bae Kim
Location 300 Longwood Avenue
Fegan-3
Boston MA 02115

Research Overview

Heung Bae Kim's research focuses on developing and testing new alternatives to existing surgical procedures. He originated the serial transverse enteroplasty, or STEP, procedure for short bowel syndrome, in which the bowel is stapled into v-shapes on alternating sides, decreasing its width and increasing its length. The procedure is currently used in instances where standard surgery to correct short-bowel syndrome is not feasible.

In addition to the STEP procedure, Dr. Kim has several areas of interest in experimental and clinical transplantation. He has developed both small and large animal models of transplant tolerance induction using In Utero bone marrow transplantation and is currently working on adapting this approach for use in postnatal organ transplantation. As the Surgical Director of the Liver, Intestine, and Kidney transplant programs, he has a keen clinical interest in improving outcomes in pediatric solid organ transplantation through immunosuppression minimization and prevention of infectious complications. Finally, through his work on a national level at the United Network for Organ Sharing (UNOS), he is involved in national clinical policy development to improve organ allocation to pediatric patients.

About Heung Bae Kim

Heung Bae Kim received his MD degree from Albert Einstein College of Medicine. He completed an internship and residency at the Hospital of the University of Pennsylvania and a fellowship at childrens Hospital Boston.

Key Publications

(For a complete list of articles on PubMed.org authored or co-authored by Dr. Kim, click here.)

  • Kim HB, Gregor MB, Boley SJ, Kleinhaus S: Digitally assisted laparoscopic drainage of multiple intraabdominal abscesses. J Laparoendoscopic Surgery 3: 477-9, 1993.
     
  • Kim HB, Raghavendran K, Kleinhaus S: Management of an abdominal cerebrospinal fluid pseudocyst using laparoscopic techniques. Surgical Laparoscopy & Endoscopy 5: 151-4, 1995.
     
  • Kim HB, Hebra A, Davidoff A, Buzby M, Maller E, Hoffman MA: Orthotopic liver transplant for inflammatory myofibroblastic tumor of the liver hilum. Journal of Pediatric Surgery 31: 840-2, 1996.
     
  • Kim HB, Shaaban AF, Yang EY, Liechty KW, Flake AW: Microchimerism and tolerance after in utero bone marrow transplantation in mice. Journal of Surgical Research 1998; 77: 1-5.
     
  • Milner R, Shaaban A, Kim HB, Fichter C, Flake AW. Postnatal booster injections increase engraftment after in utero stem cell transplantation. Journal of Surgical Research 1999; 83: 44-7.
     
  • Kim HB, Shaaban AF, Milner R, Fichter C, Flake AW: In utero bone marrow transplantation induces donor-specific tolerance by a combination of clonal deletion and clonal anergy. Journal of Pediatric Surgery 1999; 34: 726-730.
     
  • Yang EY, Kim HB, Shaaban AF, Milner R, Adzick NS, Flake AW: Persistent postnatal transgene expression in both muscle and liver after fetal injection of recombinant adenovirus. Journal of Pediatric Surgery 1999; 34: 766-773.
     
  • Shaaban AF, Kim HB, Milner R, Fichter C, Flake AW: A kinetic model for the homing and migration of prenatally transplanted marrow. Blood 1999; 94: 3251-3257.
     
  • Liechty KW, Kim HB, Adzick NS, Crombleholme TM: Fetal wound repair results in scar formation in Interleukin-10 (IL-10) deficient mice in a syngeneic murine model of scarless fetal wound repair. Journal of Pediatric Surgery 2000; 35: 866-873.
     
  • Ng E, Kim HB, Lillehei CW, Seefelder C: Life threatening tension pneumoperitoneum from intestinal perforation during air reduction of intussusception. Paediatric Anaesthesia, 12:798-800, 2002.
     
  • Kim HB, Fauza D, Garza J, Oh JT, Nurko S, Jaksic T: Serial Transverse Enteroplasty (STEP): A novel bowel lengthening procedure. Journal of Pediatric Surgery 2003; 38: 425-429.
     
  • Myers LB, Bulich LA, Mizrahi A, Barnewolt, C, Estroff J, Benson C, Kim HB, Jennings R: Ultrasonographic guidance for location of the Trachea during the EXIT procedure for cervical teratoma. Journal of Pediatric Surgery, 38: E12-E14, 2003.
     
  • Kim HB, Lee PW, Garza J, Duggan C, Fauza D, Jaksic T: Serial Transverse Enteroplasty (STEP) for short bowel syndrome: A case report. Journal of Pediatric Surgery, 38:881-885, 2003.
     
  • Fishman SJ, Jennings RW, Johnson SM, and Kim HB: Contouring buttock reconstruction after sacrococcygeal teratoma resection. Journal of Pediatric Surgery, 39: 439-441, 2004.
     
  • Downard CD, Kim HB, Laningham F, and Fishman SJ: Esophageal atresia, duodenal atresia, and unilateral lung agenesis: a case report. Journal of Pediatric Surgery, 39: 1283-1285, 2004.
     
  • DiLuozzo G, Kim HB, Boiselle PM, Colin A, Fishman SJ. Congenital absence of the right upper lobe bronchus with double segmented tracheal bronchi. Annals of Thoracic Surgery 79(1): 331-4, 2005.
     
  • Jonas MM, Krawczuk LE, Kim HB, Lillehei CW, and Perez-Atayde A. Rapid recurrence of nonalcoholic fatty liver disease after transplantation in a child with hypopituitarism and hepatopulmonary syndrome. Liver Transplantation 11(1):108-10, 2005.
     
  • Lee PW, Cina RA, Randolph MA, Goodrich J, Rowland H, Arellano R, Kim HB, Sachs DH, and Huang CA. Stable multilineage chimerism in a large animal model of in utero bone marrow transplantation. Experimental Hematology 2005; 33: 371-379.
     
  • Lee PW, Cina RA, Randolph MA, Arellano R, Goodrich J, Rowland H, Huang CA, Sachs DH, and Kim HB. In utero bone marrow transplantation induces kidney allograft tolerance across a full major histocompatibility complex barrier in swine. Transplantation 2005; 79: 1084-1090.
     
  • Javid PJ, Collier S, Richardson D, Iglesias J, Gura K, Lo C, Kim HB, Duggan CP, and Jaksic T. The Role of Enteral Nutrition in the Reversal of Parenteral Nutrition-Associated Liver Dysfunction in Infants. Journal of Pediatric Surgery 2005; 40(6): 1015-1018.
     
  • Javid PJ, Kim HB, Duggan CP, and Jaksic T. Serial Transverse Enteroplasty is Associated with Successful Short-Term Outcomes in Infants with Short Bowel Syndrome. Journal of Pediatric Surgery 2005; 40(6): 1019-1024.
     
  • Kim HB, Pomposelli JJ, Lillehei CW, Jenkins RL, Jonas MM, Krawczuk LE, and Fishman SJ. Mesogonadal Shunts for Extrahepatic Portal Vein Thrombosis and Variceal Hemorrhage. Liver Transplantation 2005; 11(11): 1389-1394.
     
  • Chang RW, Javid PJ, Oh JT, Andreoli S, Kim HB, Fauza D, and Jaksic T. Serial transverse enteroplasty enhances intestinal function in a model of short bowel syndrome. Annals of Surgery 2006; 243(2): 223-228.
     
  • Shaaban AF, Kim HB, Gaur L, Liechty KW, and Flake AW. Prenatal Transplantation of Cytokine-Stimulated Marrow Improves Early Chimerism in a Resistant Strain Combination but Results in Poor Long-Term Engraftment. Experimental Hematology, 2006; 34(9): 1278-87.
     
  • Modi BP, Langer M, Duggan C, Kim HB, and Jaksic T. Serial transverse enteroplasty for management of refractory D-lactic acidosis in short bowel syndrome. Journal of Pediatric Gastroenterology and Nutrition, 2006; 43(3): 395-397.
     
  • Duggan C, Piper H, Javid PJ, Valim C, Collier S, Kim HB, and Jaksic T. Growth and Nutritional Status in Infants with Short-Bowel Syndrome After the Serial Transverse Enteroplasty Procedure. Clinical Gastroenterology and Hepatology, 2006; 4(10): 1237-41.
     
  • Piper H, Modi BP, Kim HB, Fauza D, Glickman J, and Jaksic T. The second STEP: the feasibility of repeat serial transverse enteroplasty. Journal of Pediatric Surgery, 2006; 41(12): 1951-6.
     
  • Modi BP, Javid PJ, Jaksic T, Piper H, Langer M, Duggan C, Kamin D, and Kim HB. First report of the international serial transverse enteroplasty data registry: indications, efficacy, and complications. Journal of the American College of Surgeons, 2007; 204(3): 365-71.
     
  • Modi BP, Suh MY, Jonas MM, Lillehei C, and Kim HB. Ileal exclusion for refractory symptomatic cholestasis in Alagille syndrome. Journal of Pediatric Surgery, 2007 42(5): 800-5.
     
  • Suh MY, Wang K, Gutweiler JR, Misra MV, Krawczuk LE, Jenkins RL, Lillehei CW, Jonas MM, and Kim HB. Safety of minimal immunosuppression in liver transplantation for hepatoblastoma. Journal of Pediatric Surgery, 2008; 43(6): 1148-1152.
     
  • Gutweiler JR, LaBelle J, Suh MY, Misra MV, Ahmed M, Lee EY, Vargas SO, Kim HB, and Weldon CB. A Familial Case of Pleuropulmonary Blastoma. European Journal of Pediatric Surgery 18:192-194, 2008.