Translational Research Program
Pilot Grant Awardees
2008 - Pilot
| Principal Investigator | Affiliation | Grant Title |
|---|---|---|
| Scott Armstrong | Hematology/Oncology | Reversal of Glucocorticoid Resistance in Acute Lymphoblastic Leukemia |
| Joyce Bischoff | Vascular Biology | A stem/progenitor cell that recapitulates infantile hemangoma |
| Gabriel Corfas | Neurology | GDNF receptor agonists to treat peripheral neuropathies |
| Robert Husson | Infectious Diseases | Proteome-wide screen for M. tuberculosis antigens |
| Richard Malley | Infectious Diseases | A transcutaneous vaccine to prevent pneumococcal colonization and disease |
| Benjamin Matthews | Critical Care | Microparticles with TRPV4 inhibitor for lung protection |
| Umut Ozcan | Endocrinology | Role of ER Stress in Development of Leptin Resistance |
| Mark Puder | Surgery | The essentiality of archidonic acid (AA), docosahexaaenoic acid (DHA) |
| Leslie Silberstein | Blood Bank/Transfusion Medicine | Novel Approaches in Targeting Pediatric B-ALL |
2009 - Pilot
| Principal Investigator | Affiliation | Grant Title |
|---|---|---|
| Joyce Bischoff | Vascular Biology | A stem/progenitor cell that recapitulates infantile hemangoma |
| Wayne Lencer | Gastroenterology | Novel platform for mucosal protein drug/vaccine delivery and increased half-life |
| Luigi Notarangelo | Immunology | Use of engineered meganucleases to correct RAG1 deficiency in humans |
| Alexander Rotenberg | Neurology | Treatment of Status Epilepticus by Transcranial Direct Current Stimulation |
| Janet Soul | Neurology | Pilot Trial of Bumetanide to Treat Neonatal Seizures |
| Hanno Steen | Pathology | Urine proteomics of Kawasaki disease and pediatric vasculitis |
| Dale Umetsu | Immunology | A Novel Therapy for Severe Food Allergy by Rapid and Safe Induction of Oral Tolerance |
2010 - Pilot
| Principal Investigator | Affiliation | Grant Title |
|---|---|---|
| Xi He | Neurology | Chemical inhibition of a novel Wnt modulator for osteoporosis therapeutics |
| Jordan Kreidberg | Nephrology | c-Met inhibitor treatment of Polycystic Kidney Disease |
| David Ludwig | Endocrinology | Effects of a food preservative on glucose Homeostasis |
| Alexander Rotenberg | Neurology | Closed-loop adjustment of transcranial direct current stimulation (tDCS) in of status epilepticus |
| Dale Umetsu | Immunology | Renewal: A novel therapy for severe food allergy by rapid and safe induction of oral tolerance |
| Dennis Wall | Medicine/Informatics | Deciphering autism through cross-disease system biology |
| Gerhard Wolf | Anesthesia | Reducing ventilator-associated lung injury through non-invasive bedside imaging |
2011 - Pilot
| Principal Investigator | Affiliation | Grant Title |
|---|---|---|
| Paolo Fiorina | Medicine | Role of B7.1 in Diabetic Nephropathy |
| Rani George | Oncology | Validation of a Genetically Engineered Mouse Model of Neuroblastoma Drive by Mutated AIK and MYCN |
| Takao Hensch | Neurology | Recovery from Amblyopia with Cholinesterase Inhibitors |
| Joel Hirschhorn | Endocrinology | New Genetic Classes of Idiopathic Short Stature Defined by Sequence and Copy Number Variants |
| Robert Husson | Infectious Disease | Stress-Potential Screens to Identify Novel Inhibitors of M. Tuberculosis |
| Omar Khwaja | Neurology | Pilot Trial of Mecasermin (rDNA) Injection to Treat Rett Syndrome |
| Hannah Kinney | Pathology | Potential Clinical Biomarkers of SIDS |
| Brian Snyder | Orthopaedics | Development of Contrast Enhanced Quantitative CT as Clinical Tool for Arthritis |
2012 - Pilot
| Principal Investigator | Affiliation | Grant Title |
|---|---|---|
| William Bosl | Endocrinology | Biomarkers for Early Identification of Children with Epileptic Encephalopathies |
| Larry Benowitz | Neurosurgery | The Effects of Inosine in Promoting Recovery after Spinal Cord Injury |
| Pedro del Nido | Cardiovascular Surgery | A Novel Light-Activated Adhesive for Pediatric Cardiovascular Applications |
| Paolo Fiorina | Nephrology | Role of B7.1 in Diabetic Nephropathy: Establishing the CTLA4-lg Clinical Trial |
| Xi He | Neurology | A Novel Strategy for Turning off β-catenin Oncogenic Signaling in Cancer |
| Matthew Heeney | Hematology/Oncology | Pilot Trial of Glycine Supplementation in Autosomal Recessive Congenital Sideroblastic Anemia Due to Mutations in SLC25A38 |
| Richard Lee | Urology | Early Validation of Urinary Biomarkers of Renal Obstruction |
| Richard Malley | Infectious Disease | Development of a Multiple Antigen Presentation System (MAPS) Pneumococcal Vaccine |
| Martha Murray | Orthopaedics | Regeneration of the Anterior Cruciate Ligament after Rupture |
| Hans Oettgen | Immunology | Safe Food Allergy Desensitization using IgE Receptor Signaling Inhibitors |
| Simon Warfield | Radiology | Diffusion-Weighted MRI for the Assessment of Disease Activity and Progression in Pediatric Chron’s Disease |