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The Neuron


Go to Children's interactive feature,
The Neuron.

The neuron is the basic unit of information processing and the building block of the brain. Working together with other neurons and cells throughout the body, it allows us to think, feel, move and breathe. An electrically excitable cell, the neuron works like a minuscule computer processor, operating as a single "gate": It has a digital output (it's either on or off), and it is able to, in an instant, receive the outputs of many other cells, process this incoming information, and determine whether or not to generate its own signal -- a pulse of electrical energy. This signal is then passed on to other neurons (sometimes as many as 10,000!) or to muscle or gland cells. Even though the neuron basically passes on digital signals, it can display varying levels of excitability, firing slowly when less excited and rapidly when more excited.

This interactive feature lets you experiment with a virtual neuron to see what conditions are needed to make it fire, and it lets you experiment with a circuit of interconnected neurons (neuron circuit) to see how neurons work together to process information. The feature also provides step-through animations that illustrate how electrical currents move down the neuron along the axon (action potential) and how signals are passed on from one neuron to another (synaptic transmission).

The Neuron [400 K]
Experiment with a virtual neuron to learn how it behaves.
Requires Flash plugin.


Neuroscience Research at Children's Hospital Boston

Researcher Focus Area
Anselm, Irina, MD Mitochondrial disorders and general neurology
Bellinger, David, PhD CNS toxicity
Chen, Chinfei, MD, PhD Synaptic plasticity
Commons, Kathryn, PhD Neuroscience
Corfas, Gabriel, PhD Neuron-glia interactions
Dammann, Olaf, MD Neuroepidemiology
Darras, Basil, MD Neuromuscular disorders
Engle, Elizabeth, MD Congenital eye movement disorders
Greenberg, Michael, PhD Neuronal adaptive responses
He, Xi, PhD Wnt family
He, Zhigang, PhD, BM Axon regeneration
Hensch, Takao, PhD Critical periods in brain development
Jackson-Grusby, Laurie, PhD Epigenetic control mechanisms, Cancer stem cells
Jensen, Frances, MD Hypoxic/ischemic perinatal brain injury
Kang, Peter, MD Variations in muscle gene expression
Leviton, Alan, MD Epidemiology of brain damage in preterm newborns
Kreiman, Gabriel, PhD, MSc Architecture of neuronal circuits
Pomeroy, Scott, MD, PhD Molecular biology of meduloblastoma
Rosenberg, Paul, MD, PhD Glutamate transport
Sahin, Mustafa, MD, PhD Axon guidance
Rivkin, Michael, MD Cognitive disorders and brain development
Rosenberg, Paul, MD, PhD Glutamate transport
Sahin, Mustafa, MD, PhD Axon guidance
Soul, Janet, MD Brain injury in premature infants
Volpe, Joseph, MD Brain injury in premature infants

Credits: The Neuron
Subject Matter Experts:   Gabriel Kreiman, PhD
Kathryn Commons, PhD
Producer/Writer: Rick Groleau
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