The Melero-Martin Lab
Welcome to the Melero-Martin Laboratory, a Bioengineering and Cell Biology lab within the Department of Cardiac Surgery at the Children's Hospital, Boston. We are affiliated with the Harvard Medical School.
Tissue Engineering holds great promise in regenerative medicine as an alternative approach to replace diseased and damaged tissues. A challenge in tissue engineering is to generate tissues with a functional vascular bed. Our lab is interested in developing cell-based strategies to generate both vascular networks and vascularized tissues using human postnatal cells.
bioengineering human vascular networks...
Three Most Recent Publications
Equal modulation of endothelial cell function by four distinct tissue-specific mesenchymal stem cells. Lin RZ, Moreno-Luna R, Zhou B, Pu WT, Melero-Martin JM. Angiogenesis 2012; 15(3):443-55. PDF
Fibroblast growth factor-2 facilitates rapid anastomosis formation between bioengineered human vascular networks and living vasculature. Lin RZ, Melero-Martin JM. Methods 2012; 56(3):440-51. PDF
Functional human vascular network generated in photocrosslinkable gelatin methacrylate hydrogels. Chen YC+, Lin RZ+, Qi H, Yang Y, Bae H, Melero-Martin JM*, Khademhosseini A*. Adv Funct Mater 2012; 22(10): 2027-39. (+co-first authors; * co-corresponding authors) PDF
IN THE NEWS
Nov 22, 2011 − Nancy Fliesler (VECTOR)
Nov 15, 2011 − Children’s Hospital Boston, Newsroom
Oct 13, 2011 − Science-Business exchange (SciBX) PDF
May 12, 2011 − Cell Transplantation Center of Excellence for Aging and Brain Repair
February 8, 2011 - Maude Tessier (VECTOR)