Susan Chi, MD

Research Overview

Dr. Chi's clinical research focuses primarily on pediatric brain tumors, specifically in malignant infant tumors such as atypical teratoid rhabdoid tumors (ATRT), high risk medulloblastoma and choroid plexus tumors.

About Susan Chi, MD

After graduating from Princeton University, Dr. Chi received her medical degree from Mount Sinai School of Medicine (New York, NY) and completed her pediatric residency at Yale/New Haven Hospital (New Haven, CT). After an additional chief residency year in New Haven, she then completed a Pediatric Hematology-Oncology fellowship at Memorial Sloan-Kettering Cancer Center (New York, NY), followed by a pediatric and adult neuro-oncology fellowship at NYU Medical Center (New York, NY).

Key Publications

• Fleming AJ and Chi SN. Brain tumors in children. Curr Probl Pediatr Adolesc Health Care 2012; 42:80-103.

• Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, Olson JM, Geyer JR, Chi SN, da Silva NS, Onar-Thomas A, Baker JN, Gajjar A, Ellison DW, Baker SJ. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsiv pontine glioma. J Clin Oncol 2011; 29: 3999-4006.
   
• Broniscer A, Baker JN, Baker SJ, Chi SN, Geyer JR, Morris EB, Gajjar A. Prospective collection of tissue samples at autopsy in children with diffuse intrinsic pontine glioma. Cancer 2010; Jun 29.
   
• Gururangan S, Chi SN, Young Poussaint T, Onar-Thomas A, Gilbertson RJ, Vajapeyam S, Friedman HS, Packer RJ, Rood BN, Boyett JM, Kun LE. Lack of efficacy of bevacizumab plus irinotecan in children with recurrent malignant glioma and diffuse brainstem glioma: a Pediatric Brain Tumor Consortium study. J Clin Oncol 2010; 28: 3069-75.
   
• Chi SN, Zimmerman MA, Yao X, Cohen KJ, Burger P, Biegel JA, Rorke-Adams LB, Fisher MJ, Janss A, Mazewski C, Goldman S, Manley PE, Bowers DC, Bendel A, Rubin J, Turner CD, Marcus KJ, Goumnerova L, Ullrich NJ, Kieran MW. Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. J Clin Oncol 2009; 27: 385-389.
   
• Fangusaro J and Chi S. Introduction to a special issue on pediatric neuro-oncology. Journal Child Neurology 2009; 11:1341-2.
   
• Zacharoulis S, Levy A, Chi SN, Gardner S, Rosenblum M, Miller DC, Dunkel I, Diez B, Sposto R, Ji L, Asgharzadeh S, Hukin J, Belasco J, Dubowy R, Kellie S, Termuhlen A, Finlay J. Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue Pediatr Blood Cancer 2007; 49:34-40.
   
• Kieran MW, Turner CD, Rubin JB, Chi SN, Zimmerman MA, Chordas C, Klement G, Laforme A, Gordon A, Thomas A, Neuberg D, Browder T, Folkman J. A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer. J Pediatr Hematol Oncol. 2005; 27:573-81.
   
• Zimmerman MA, Goumnerova LC, Proctor M, Scott RM, Marcus K, Pomeroy SL, Turner CD, Chi SN, Chordas C and Kieran MW. Continuous remission of newly diagnosed and relapsed central nervous system atypical teratoid/rhabdoid tumor. J Neuro-oncol 2005; 72-77-84.
   
• Chi SN, Gardner SL, Levy AS, Knopp EA, Miller DC, Wisoff JH, Weiner HL, Finlay JF. Feasibility and response to induction chemotherapy intensified with high-dose methotrexate for young children with newly diagnosed high-risk disseminated medulloblastoma. J Clin Oncol. 2004; 22:4881-7.