Boston Children's Hospital's Division of Nephrology's Research Program is directed by Mohamed Sayegh, MD, and is involved in both basic and clinical research in transplantation biology, renal development, and nephrotic syndrome, particularly focal glomerulosclerosis and autosomal recessive polycystic disease of the kidney.
The Division of Nephrology is dedicated to developing lasting treatments for the most serious kidney diseases affecting children. It has established a Transplantation Research Center in collaboration with the Brigham and Women's Hospital with an ultimate goal of developing tolerance protocols for organ transplant recipients. Children's researchers in nephrology are also investigating the vascular component of the immune response with an eye toward new immunosuppression protocols. The Division has developed the largest and most active kidney transplant clinical trials group in the country in order to transfer such discoveries from the bench to the bedside.
Recognizing that developmental anomalies are responsible for over 50% of the causes of kidney failure in children, the division has assembled a very large developmental and regenerative biology team. And, in order to take advantage of the remarkable breakthroughs of modern genomics, Nephrology is developing a pharmacogenomics group.
Featured researchers in the Division of Nephrology hold faculty appointments at Harvard Medical School.
|Briscoe, David, MD||Transplant rejection|
|William Harmon, MD||Pediatric kidney transplantation|
|John Herrin, MBBS||Kidney transplantation|
|Jordan Kreidberg, MD, PhD||Stem cells for kidney failure|
|Mohamed Sayegh, MD||Kidney transplantation|
|Asher Schachter, MD, MMSc, MS||Transplant genomics and proteomics|