Pediatric Critical Care Nutrition

Dr. Mehta is the Principal Investigator of 2 large international studies of nutrient delivery in mechanically ventilated children. The results of the first study have now been published. (Crit Care Med. 2012 Jul;40(7):2204-11)

The 2nd International study of nutrition practice in mechanically ventilated children started on May 11, 2011. We had a large number of returning and new sites this year. Data entry was completed on Jan 31st 2012. Over 60 sites completed data collection with more than 1200 subjects enrolled. The study is now closed for data entry. Data cleaning is complete.  Participating pediatric ICUs will soon receive a benchmarked, individualized site-report, which will allow comparison of practice at each center with the rest of the international cohort. 

The 2nd International study of nutrition practice in mechanically ventilated children started on May 11, 2011. We had a large number of returning and new sites this year. Data entry was completed on Jan 31st 2012. Over 60 sites completed data collection with more than 1200 subjects enrolled. The study is now closed for data entry and data cleaning is complete. Participating pediatric ICU's received a bench marked, individualized site-report in December 2012 which allowed comparison of practice at each center with the rest of the international cohort. Please review the report and consider ways to disseminate the observations among key stake holders,and identify areas in which your site practice could be further improved. We will be happy to help or suggest ways in which previous sites have utilized these reports. We are extremely grateful for your overwhelming participation and are positive that this collaborative effort will significantly help enhance the quality of bedside nutrition therapy in our PICU's.

1. Mehta NM, Bechard LJ, Cahill N, Wang M, Day A, Duggan CP, Heyland DK.  Nutritional practices and their relationship to clinical outcomes in critically ill children–an international multicenter cohort study. Crit Care Med. 2012 Jul;40(7):2204-11.
2. Smallwood C, Mehta NM. Accuracy of abbreviated indirect calorimetry protocols for energy expenditure measurement in critically ill children. JPEN J Parenter Enteral Nutr. 2012 Nov;36(6):693-699.  
3.  Mehta NM, Costello JM, Bechard LJ, Johnson VM, Zurakowski D, McGowan FX, Laussen PC, Duggan CP.Resting Energy Expenditure After Fontan Surgery in Children With Single-Ventricle Heart Defects. JPEN J Parenter Enteral Nutr. 2012 Nov;36(6):685-692
4. Skillman HE, Mehta NM. Nutrition therapy in the critically ill child. Curr Opin Crit Care. 2012 Apr;18(2):192-8.
5. Bechard LJ, Parrott JS, Mehta NM.  Systematic review of energy and protein intake on protein balance in critically ill children. J Pediatr. 2012 Aug;161(2):333-339.
6. Bechard LJ, Feldman HA, Venick R, Gura K, Gordon CM, Sonis A, Mehta NM, Guinan EC, Duggan C.  Attenuation of resting energy expenditure following hematopoietic stem cell transplantation in children.  Bone Marrow Transplant. 2012 Feb 20. doi: 10.1038/bmt.2012.19. [Epub].
7. Mehta NM. The Goldilocks conundrum for optimal macronutrient delivery in the PICU – too much, too little or just right? JPEN (in press).
8. Bechard LJ, Feldman HA, Venick R, Gura K, Gordon C, Sonis A, Mehta N, Guinan EC, Duggan C. Attenuation of resting energy expenditure following hematopoietic SCT in children. Bone Marrow Transplant 2012 Oct;47(10):1301-1306.