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Liberating clinical trial data

Clinical trial data is ends up locked away in proprietary databases, making it difficult (if not impossible) to engage the broader scientific and biotechnology/pharma community in asking new questions or answering unsolved problems. Kenneth Mandl, MD, MPH, of Boston Children's Hospital's Informatics Program advocates taking a page from the open source softward communtiy and making de-identified clinical trial data available to all. (Image: Wikimedia Commons) [Read more]

Recent basic/translational research

Seizure detection: it's all in the wrist

Tobias Loddenkemper, MD, in Boston Children's Epilepsy Program, is using a sensor-laden wristband that can detect convulsive movements and nervous system activity to better understand patterns of seizure activity in children with epilepsy. [Read more]

 

Being PRUDENT about transfusions

There are many reasons why a child might need a blood transfusion, but little science behind the guidelines used to decide when the time is right. A team of physicians from across Boston Chldren's Hospital, called PRUDENT, came together to take a hard initial look at transfusion practices throughout the hospital and develop better, evidence-based, cost-effective criteria that improve the quality of care. (Image: @alviseni/Flickr) [Read more]

 

Taking a targeted approach when leukemia comes back

Lewis Silverman, MD, director of the Pediatric Hematologic Malignancy Service at Dana-Farber/Children’s Hospital Cancer Center, thinks he may have a powerful new strategy for treating children with relapsed acute lymphoblastic leukemia (ALL) that tears down the barriers these ALL cells erect against corticosteroids. (Image: VashiDonsk/Wikimedia Commons) [Read more]

 

Check out our timeline of Recent Advances and Featured Science and Innovations.

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