The Division of Immunology has a long track record of cutting edge research in allergic and immunological mechanisms and is recognized world-wide for work on IgE regulation, Current areas of basic research include:
- Pathogenesis of atopic dermatitis
- Wiskott Aldrich Syndrome protein (WASP) and associated molecules
- Signal transduction by the T cell receptor, the role of SLP-76
- Regulation of IgE production
- Roles of IgE in allergic pathogenesis and parasite immunity
- TRAF functions in TNF receptor family signaling
Ongoing clinical projects include:
- The evaluation of immunomodulators in asthma and atopic dermatitis.
- A study of the efficacy of purified C1 esterase inhibitor in hereditary angioneurotic edema.
- The evaluation of intravenous gammaglobulin treatment of patients with antibody deficiency disorders.
- Studies of the use of anti_IgE in the treatment of asthma and atopic dermatitis.
Featured researchers in the Division of Immunology hold faculty appointments at Harvard Medical School.
Latest Research in Immunology:
|Raif Geha, MD||Immune deficiencies|
|Luigi Daniele Notarangelo, MD||Cellular bases of congenital immunodeficiencies|
|Hans Oettgen, MD, PhD||Allergy|
|Narayanaswamy Ramesh, PhD||Molecular basis of primary immunodeficiencies|
|Lynda Schneider, MD||Allergy|
|Dale T. Umetsu, MD, PhD||The immunobiology of asthma and allergy|