Infectious Diseases
Research in the Division of Infectious Diseases includes both basic investigation and clinical research. The bench research in the division has the broad objective of elucidating basic mechanisms of microbial pathogenesis and the related host responses that mediate susceptibility to infection, host injury, and protective immunity. Investigation targets viral, bacterial, fungal, and parasitic pathogens of major significance in community acquired infections in the United States, in infections of immunocompromised hosts, and in global public health. Current projects include:
- Pathogen-host signaling in streptococcal infection
- Novel strategies for pneumococcal vaccines
- Enhancing innate and adaptive immunity in neonates
- Regulation of bacterial virulence gene expression
- Modeling cholera infection and host responses in Drosophila
- HIV pathogenesis, immune response, and vaccine development
- Regulation of morphogenesis in Candida albicans
- Molecular approaches to malaria pathogenesis
Clinical research is focused in two broad areas: clinical trials in pediatric HIV and clinical epidemiology/clinical decision-making.
Researchers in the Division of Infectious Diseases hold faculty appointments at Harvard Medical School.
Latest Research in Infectious Diseases:
| Researcher | Focus Area |
|---|---|
| Asim A. Ahmed, MD | tk |
| Anna Aldovini, MD | HIV biology |
| Sandra Burchett, MD, MS | Viral infections |
| Simon Dove, PhD | Transcription regulation |
| Jeffrey Dvorin, MD, PhD | Malaria, Parasitology, Tropical Medicine |
| Elizabeth Egan, MD, PhD | Infectious Diseases |
| Courtney Gidengil, MD, MPH | Pediatric Health Services Research |
| Donald Goldmann, MD | Bacterial Infection |
| Ioannis Gryllos, PhD | Pathogenesis mechanisms of group A Streptococcus |
| Robert N. Husson, MD | Molecular pathogenesis of mycobacterial infection |
| Julia R. Koehler, MD | Infectious Diseases |
| Grace M. Lee, MD, MPH | Vaccine policy, Infectious disease epidemiology |
| Katherine P. Lemon, MD, PhD | Human Upper Respiratory Tract Microbiome |
| Ofer Levy, MD, PhD | Innate immunity of the human newborn |
| Yingjie Lu, PhD | vaccine development for infectious disease |
| Richard Malley, MD | Pneumococcal pathogenesis and immunity, vaccine development |
| Charlotte Mao, MD, MPH | Pediatric HIV clinical trials |
| Kenneth McIntosh, MD | HIV and viral infections |
| John N. Misasi, MD | Emerging virus entry mechanisms and pathogenesis |
| Kristin Moffitt, MD | Host bacterial pathogen interactions, Bacterial vaccine development |
| Mari Nakamura, MD, MPH | Vaccine health services research, Health information technology |
| Gregory Priebe, MD | Pseudomonas aeruginosa infections |
| Thomas J. Sandora, MD, MPH | Hospital epidemiology, Hand hygiene |
| Tanvi Sharma, MD | Pediatric HIV, Immunocompromised infectious diseases |
| Paula I. Watnick, MD, PhD | Bacterial adhesion to surfaces; enteric pathogens |
| Michael R. Wessels, MD | Streptococcus infection |
Infectious Diseases
