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Recent Publications

Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice

Chai, Cui, et al. Nature Medicine 2023
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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Cui, et al. Nature Communications 2021
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Dynamic transcriptional responses to injury of regenerative and non-regenerative cardiomyocytes revealed by single-nucleus RNA sequencing

Cui, et al. Developmental Cell, 2020
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All Publications

  1. Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice

    Chai AC, Cui M, Chemello F, Li H, Chen K, Tan W, Atmanli A, McAnally JR, Zhang Y, Xu L, Liu N, Bassel-Duby R, Olson EN. Nat Med. 2023 Feb;29(2):401-411. PMID: 36797478

  2. Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy

    Nishiyama T, Zhang Y, Cui M, Li H, Sanchez-Ortiz E, McAnally JR, Tan W, Kim J, Chen K, Xu L, Bassel-Duby R, Olson EN. Sci Transl Med. 2022 Nov 23;14(672):eade1633. doi: 10.1126/scitranslmed.ade1633. Epub 2022 Nov 23. PubMed PMID: 36417486; PubMed Central PMCID: PMC10088465.

  3. Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

    Cui M, Atmanli A, Morales MG, Tan W, Chen K, Xiao X, Xu L, Liu N, Bassel-Duby R, Olson EN. Nat Commun. 2021 Sep 6;12(1):5270. doi: 10.1038/s41467-021-25653-w. PubMed PMID: 34489413; PubMed Central PMCID: PMC8421386.

  4. Cardiac Myoediting Attenuates Cardiac Abnormalities in Human and Mouse Models of Duchenne Muscular Dystrophy

    Atmanli A, Chai AC, Cui M, Wang Z, Nishiyama T, Bassel-Duby R, Olson EN. Circ Res. 2021 Sep 3;129(6):602-616. doi: 10.1161/CIRCRESAHA.121.319579. Epub 2021 Aug 10. PubMed PMID: 34372664; PubMed Central PMCID: PMC8416801.

  5. Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution

    Wang Z, Cui M, Shah AM, Tan W, Liu N, Bassel-Duby R, Olson EN. Cell Rep. 2021 May 25;35(8):109211. doi: 10.1016/j.celrep.2021.109211. PubMed PMID: 34038730; PubMed Central PMCID: PMC8210827.

  6. miRNA-independent function of long noncoding pri-miRNA loci

    He D, Wu D, Muller S, Wang L, Saha P, Ahanger SH, Liu SJ, Cui M, Hong SJ, Jain M, Olson HE, Akeson M, Costello JF, Diaz A, Lim DA. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13). doi: 10.1073/pnas.2017562118. PubMed PMID: 33758101; PubMed Central PMCID: PMC8020771.

  7. Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing

    Cui M, Wang Z, Chen K, Shah AM, Tan W, Duan L, Sanchez-Ortiz E, Li H, Xu L, Liu N, Bassel-Duby R, Olson EN. Dev Cell. 2020 Apr 6;53(1):102-116.e8. doi: 10.1016/j.devcel.2020.02.019. Epub 2020 Mar 26. PubMed PMID: 32220304; PubMed Central PMCID: PMC7365574.

  8. Protocol for Single-Nucleus Transcriptomics of Diploid and Tetraploid Cardiomyocytes in Murine Hearts

    Cui M, Olson EN. STAR Protoc. 2020 Sep 18;1(2):100049. doi: 10.1016/j.xpro.2020.100049. eCollection 2020 Sep 18. PubMed PMID: 33111095; PubMed Central PMCID: PMC7580205.

  9. Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling

    Wang Z, Cui M, Shah AM, Ye W, Tan W, Min YL, Botten GA, Shelton JM, Liu N, Bassel-Duby R, Olson EN. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18455-18465. doi: 10.1073/pnas.1905824116. Epub 2019 Aug 26. PubMed PMID: 31451669; PubMed Central PMCID: PMC6744882. *co-first author

  10. The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo

    Andersen RE, Hong SJ, Lim JJ, Cui M, Harpur BA, Hwang E, Delgado RN, Ramos AD, Liu SJ, Blencowe BJ, Lim DA. Dev Cell. 2019 May 20;49(4):632-642.e7. doi: 10.1016/j.devcel.2019.04.032. PubMed PMID: 31112699; PubMed Central PMCID: PMC6556063.

  11. Genetic and epigenetic regulation of cardiomyocytes in development, regeneration and disease

    Cui M, Wang Z, Bassel-Duby R, Olson EN. Development. 2018 Dec 20;145(24). doi: 10.1242/dev.171983. Review. PubMed PMID: 30573475; PubMed Central PMCID: PMC6307883.

  12. Identification of a multipotent Twist2-expressing cell population in the adult heart

    Min YL, Jaichander P, Sanchez-Ortiz E, Bezprozvannaya S, Malladi VS, Cui M, Wang Z, Bassel-Duby R, Olson EN, Liu N. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8430-E8439. doi: 10.1073/pnas.1800526115. Epub 2018 Aug 20. PubMed PMID: 30127033; PubMed Central PMCID: PMC6130356.

  13. Recent advances in functional perturbation and genome editing techniques in studying sea urchin development

    Cui M, Lin CY, Su YH. Brief Funct Genomics. 2017 Sep 1;16(5):309-318. doi: 10.1093/bfgp/elx011. Review. PubMed PMID: 28605407.

  14. Sequential Response to Multiple Developmental Network Circuits Encoded in an Intronic cis-Regulatory Module of Sea Urchin hox11/13b

    Cui M*, Vielmas E, Davidson EH, Peter IS. Cell Rep. 2017 Apr 11;19(2):364-374. doi: 10.1016/j.celrep.2017.03.039. PubMed PMID: 28402858. *corresponding author

  15. Specific functions of the Wnt signaling system in gene regulatory networks throughout the early sea urchin embryo

    Cui M, Siriwon N, Li E, Davidson EH, Peter IS. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5029-38. doi: 10.1073/pnas.1419141111. Epub 2014 Nov 10. PubMed PMID: 25385617; PubMed Central PMCID: PMC4250154.

  16. Encoding regulatory state boundaries in the pregastrular oral ectoderm of the sea urchin embryo

    Li E, Cui M, Peter IS, Davidson EH. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E906-13. doi: 10.1073/pnas.1323105111. Epub 2014 Feb 20. PubMed PMID: 24556994; PubMed Central PMCID: PMC3956148.