Alvin Kho

Publications

1. Peripheral blood miRNAs are associated with airflow below threshold in children with asthma. Respir Res. 2025 Jan 24; 26(1):38. View Abstract
2. Circulating microRNAs associated with bronchodilator response in childhood asthma. BMC Pulm Med. 2024 Nov 04; 24(1):553. View Abstract
3. MiR-107 and Its Association With House Dust Mite Sensitisation: Implications for Asthma. Clin Exp Allergy. 2025 Jan; 55(1):67-74. View Abstract
4. Enhancing Asthma Pharmacogenetics Through Subtype-Specific Associations. Clin Exp Allergy. 2024 Oct 02. View Abstract
5. Specific microRNA Profile Associated with Inflammation and Lipid Metabolism for Stratifying Allergic Asthma Severity. Int J Mol Sci. 2024 Aug 30; 25(17). View Abstract
6. Identification of MicroRNAs in children with increased asthma bronchodilator usage in genetics of asthma in Costa Rica Study. Pediatr Pulmonol. 2024 Dec; 59(12):3491-3498. View Abstract
7. piRNA associates with immune diseases. Cell Commun Signal. 2024 Jun 28; 22(1):347. View Abstract
8. GSDMB/ORMDL3 Rare/Common Variants Are Associated with Inhaled Corticosteroid Response among Children with Asthma. Genes (Basel). 2024 03 28; 15(4). View Abstract
9. Circulating miRNAs associate with historical childhood asthma hospitalization in different serum vitamin D groups. Respir Res. 2024 Mar 08; 25(1):118. View Abstract
10. A novel piwi-interacting RNA associates with type 2-high asthma phenotypes. J Allergy Clin Immunol. 2024 Mar; 153(3):695-704. View Abstract
11. Circulating MicroRNAs associated with Bronchodilator Response in Childhood Asthma. Res Sq. 2023 Jun 29. View Abstract
12. Systems Genomics Reveals microRNA Regulation of ICS Response in Childhood Asthma. Cells. 2023 05 29; 12(11). View Abstract
13. Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients. Cell Rep Med. 2023 06 20; 4(6):101079. View Abstract
14. Intrauterine Smoke Exposure, microRNA Expression during Human Lung Development, and Childhood Asthma. Int J Mol Sci. 2023 Apr 23; 24(9). View Abstract
15. Antagonizing cholecystokinin A receptor in the lung attenuates obesity-induced airway hyperresponsiveness. Nat Commun. 2023 01 04; 14(1):47. View Abstract
16. Blood miRNAs Are Linked to Frequent Asthma Exacerbations in Childhood Asthma and Adult COPD. Noncoding RNA. 2022 Apr 03; 8(2). View Abstract
17. Lung function, airway and peripheral basophils and eosinophils are associated with molecular pharmacogenomic endotypes of steroid response in severe asthma. Thorax. 2022 05; 77(5):452-460. View Abstract
18. Seasonal Variation in miR-328-3p and let-7d-3p Are Associated With Seasonal Allergies and Asthma Symptoms in Children. Allergy Asthma Immunol Res. 2021 Jul; 13(4):576-588. View Abstract
19. Commercially Available Blocking Oligonucleotides Effectively Suppress Unwanted Hemolysis-Related miRNAs in a Large Whole-Blood RNA Cohort. J Mol Diagn. 2021 06; 23(6):671-682. View Abstract
20. Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification. J Pers Med. 2021 Apr 16; 11(4). View Abstract
21. Drug Repurposing to Treat Glucocorticoid Resistance in Asthma. J Pers Med. 2021 Mar 03; 11(3). View Abstract
22. COPD-associated miR-145-5p is downregulated in early-decline FEV1 trajectories in childhood asthma. J Allergy Clin Immunol. 2021 06; 147(6):2181-2190. View Abstract
23. Effect of Intrauterine Smoke Exposure on microRNA-15a Expression in Human Lung Development and Subsequent Asthma Risk. Healthcare (Basel). 2020 Dec 04; 8(4). View Abstract
24. Co-methylation analysis in lung tissue identifies pathways for fetal origins of COPD. Eur Respir J. 2020 10; 56(4). View Abstract
25. Enhancing the prediction of childhood asthma remission: Integrating clinical factors with microRNAs. J Allergy Clin Immunol. 2021 03; 147(3):1093-1095.e1. View Abstract
26. CASTER: Cross-Sectional Asthma STEroid Response Measurement. J Pers Med. 2020 Aug 20; 10(3). View Abstract
27. Circulating MicroRNAs and Treatment Response in Childhood Asthma. Am J Respir Crit Care Med. 2020 07 01; 202(1):65-72. View Abstract
28. COMPSRA: a COMprehensive Platform for Small RNA-Seq data Analysis. Sci Rep. 2020 03 12; 10(1):4552. View Abstract
29. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Med. 2020 03 02; 12(1):25. View Abstract
30. Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. Respir Res. 2020 Jan 28; 21(1):31. View Abstract
31. Mechanical forces induce an asthma gene signature in healthy airway epithelial cells. Sci Rep. 2020 01 22; 10(1):966. View Abstract
32. Pulmonary Neuroendocrine Cells Secrete ?-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models. Am J Respir Cell Mol Biol. 2019 06; 60(6):687-694. View Abstract
33. Whole exome sequencing analysis in severe chronic obstructive pulmonary disease. Hum Mol Genet. 2018 11 01; 27(21):3801-3812. View Abstract
34. Circulating microRNAs and prediction of asthma exacerbation in childhood asthma. Respir Res. 2018 06 26; 19(1):128. View Abstract
35. Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort. PLoS One. 2017; 12(7):e0180329. View Abstract
36. Zinc deficiency primes the lung for ventilator-induced injury. JCI Insight. 2017 Jun 02; 2(11). View Abstract
37. Asthma remission: Predicting future airways responsiveness using an miRNA network. J Allergy Clin Immunol. 2017 08; 140(2):598-600.e8. View Abstract
38. Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. Am J Respir Crit Care Med. 2016 12 15; 194(12):1465-1474. View Abstract
39. CRISPLD2 (LGL1) inhibits proinflammatory mediators in human fetal, adult, and COPD lung fibroblasts and epithelial cells. Physiol Rep. 2016 09; 4(17). View Abstract
40. Temporal dynamics of the developing lung transcriptome in three common inbred strains of laboratory mice reveals multiple stages of postnatal alveolar development. PeerJ. 2016; 4:e2318. View Abstract
41. Circulating MicroRNAs: Association with Lung Function in Asthma. PLoS One. 2016; 11(6):e0157998. View Abstract
42. Age, Sexual Dimorphism, and Disease Associations in the Developing Human Fetal Lung Transcriptome. Am J Respir Cell Mol Biol. 2016 06; 54(6):814-21. View Abstract
43. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12; 374(19):1842-1852. View Abstract
44. Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures. Mol Cell Proteomics. 2016 06; 15(6):1877-94. View Abstract
45. Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures. Mol Autism. 2015; 6:66. View Abstract
46. Steroid Pathway Genes and Neonatal Respiratory Distress After Betamethasone Use in Anticipated Preterm Birth. Reprod Sci. 2016 May; 23(5):680-6. View Abstract
47. Unjamming and cell shape in the asthmatic airway epithelium. Nat Mater. 2015 Oct; 14(10):1040-8. View Abstract
48. Glucocorticoid genes and the developmental origins of asthma susceptibility and treatment response. Am J Respir Cell Mol Biol. 2015 May; 52(5):543-53. View Abstract
49. Fetal lung and placental methylation is associated with in utero nicotine exposure. Epigenetics. 2014 Nov; 9(11):1473-84. View Abstract
50. Genetic variation in the HLA region is associated with susceptibility to herpes zoster. Genes Immun. 2015 Jan-Feb; 16(1):1-7. View Abstract
51. The genomic origins of asthma. Thorax. 2014 May; 69(5):481-7. View Abstract
52. Vitamin D related genes in lung development and asthma pathogenesis. BMC Med Genomics. 2013 Nov 05; 6:47. View Abstract
53. Identification of dedifferentiation and redevelopment phases during postpneumonectomy lung growth. Am J Physiol Lung Cell Mol Physiol. 2013 Oct 15; 305(8):L542-54. View Abstract
54. MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation. Cell Death Differ. 2013 Sep; 20(9):1194-208. View Abstract
55. Cell elasticity determines macrophage function. PLoS One. 2012; 7(9):e41024. View Abstract
56. Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normoresponsive rat pups. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15; 303(10):L899-911. View Abstract
57. Expression analysis of asthma candidate genes during human and murine lung development. Respir Res. 2011 Jun 23; 12:86. View Abstract
58. Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors. Muscle Nerve. 2011 May; 43(5):741-50. View Abstract
59. Proteomic temporal profile of human brain endothelium after oxidative stress. Stroke. 2011 Jan; 42(1):37-43. View Abstract
60. Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression. J Cell Biol. 2010 Aug 23; 190(4):693-706. View Abstract
61. Genetic influences on asthma susceptibility in the developing lung. Am J Respir Cell Mol Biol. 2010 Dec; 43(6):720-30. View Abstract
62. An EGFR autocrine loop encodes a slow-reacting but dominant mode of mechanotransduction in a polarized epithelium. FASEB J. 2010 May; 24(5):1604-15. View Abstract
63. Transcriptomic analysis of human lung development. Am J Respir Crit Care Med. 2010 Jan 01; 181(1):54-63. View Abstract
64. Platform dependence of inference on gene-wise and gene-set involvement in human lung development. BMC Bioinformatics. 2009 Jun 19; 10:189. View Abstract
65. Transcriptional regulation differs in affected facioscapulohumeral muscular dystrophy patients compared to asymptomatic related carriers. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6220-5. View Abstract
66. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 2008 Aug 12; 14(2):123-34. View Abstract
67. Expression profiles of the mouse lung identify a molecular signature of time-to-birth. Am J Respir Cell Mol Biol. 2009 Jan; 40(1):47-57. View Abstract
68. High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis. Arthritis Res Ther. 2007; 9(2):R36. View Abstract
69. Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin. J Cell Biol. 2006 Oct 09; 175(1):99-110. View Abstract
70. Cerebellar 'transcriptome' reveals cell-type and stage-specific expression during postnatal development and tumorigenesis. Mol Cell Neurosci. 2006 Nov; 33(3):247-59. View Abstract
71. Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model. J Proteome Res. 2006 Aug; 5(8):1866-78. View Abstract
72. Melanoma cell adhesion molecule is a novel marker for human fetal myogenic cells and affects myoblast fusion. J Cell Sci. 2006 Aug 01; 119(Pt 15):3117-27. View Abstract
73. Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development. PLoS Med. 2006 Jul; 3(7):e232. View Abstract
74. Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia. Stem Cells. 2006 Sep; 24(9):2034-44. View Abstract
75. Transcriptome-scale similarities between mouse and human skeletal muscles with normal and myopathic phenotypes. BMC Musculoskelet Disord. 2006 Mar 07; 7:23. View Abstract
76. Melanoma Cell Adhesion Molecule is a novel marker for human fetal myogenic cells and affects myoblast fusion. J Cell Sci. 119, 3117-27, 2006. 2006; 119(Pt 15):3117-27. View Abstract
77. Alteration of ribosomal protein gene expression, transcription, apoptosis and cancer pathways in Diamond-Blackfan anemia. Stem Cells. 2006; 24(9):2033-44. View Abstract
78. The influence of muscle type and dystrophin deficiency on murine expression profiles. Mamm Genome. 2005 Oct; 16(10):739-48. View Abstract
79. Variations in gene expression among different types of human skeletal muscle. Muscle Nerve. 2005 Oct; 32(4):483-91. View Abstract
80. Side population cells isolated from different tissues share transcriptome signatures and express tissue-specific markers. Exp Cell Res. 2005 Feb 15; 303(2):360-74. View Abstract
81. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol. 2004 May; 63(5):499-509. View Abstract
82. Molecular classification of nemaline myopathies: "nontyping" specimens exhibit unique patterns of gene expression. Neurobiol Dis. 2004 Apr; 15(3):590-600. View Abstract
83. Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. Genes Dev. 2004 Mar 15; 18(6):629-40. View Abstract
84. Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing. J Biol Chem. 2003 Dec 12; 278(50):50466-73. View Abstract
85. Gene expression profiling of Duchenne muscular dystrophy skeletal muscle. Neurogenetics. 2003 Aug; 4(4):163-71. View Abstract
86. Expression profiling reveals altered satellite cell numbers and glycolytic enzyme transcription in nemaline myopathy muscle. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4666-71. View Abstract
87. Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):15000-5. View Abstract
88. Microarrays for an Integrative Genomics. 2002; 326. View Abstract
89. Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach. Proc Natl Acad Sci U S A. 2002 Apr 16; 99(8):5704-9. View Abstract
90. CHIP TUNER: a web tool for evidence-based noise reduction in gene discovery. Proc AMIA Symp. 2002; 810-4. View Abstract
91. Stochastic mean curvature flows: Asymptotic derivation, level set formulation and numerics. Interfaces and Free Boundaries. 2001; 3:265-90. View Abstract
92. Multi-scale analysis for microscropic models in materials science and cell biology. 2000. View Abstract
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