Information

Related Research Units

Gastroenterology, Hepatology and Nutrition Research

Education

Undergraduate School

Harvard University
1994 Cambridge MA

Medical School

Dartmouth Medical School
1998 Hanover NH

Internship

Duke University Medical Center
1999 Durham MA

Residency

Duke University Medical Center
2001 Durham NC

Fellowship

Boston Children's Hospital
2004 Boston MA

Media

Caregiver Profile

Meet Dr. Rachel Rosen

Publications

  1. Outcomes for infants with BRUE diagnosed with oropharyngeal dysphagia or gastroesophageal reflux disease: a multicenter study from the Pediatric Health Information System Database. Eur J Pediatr. 2025 Jan 14; 184(2):134. View Abstract
  2. Prevalence and Trends in Cigarette Smoking With and Without Tobacco Use Disorder Among Adults in the United States: 2010-2021. J Clin Psychiatry. 2024 Jun 12; 85(3). View Abstract
  3. Brief Resolved Unexplained Events Symptoms Frequently Result in Inappropriate Gastrointestinal Diagnoses and Treatment. J Pediatr. 2024 Sep; 272:114128. View Abstract
  4. Transpyloric feeding is associated with adverse in-hospital outcomes in infants with severe bronchopulmonary dysplasia. J Perinatol. 2024 02; 44(2):307-313. View Abstract
  5. Breastfeeding in infants who aspirate may increase risk of pulmonary inflammation. Pediatr Pulmonol. 2024 Mar; 59(3):600-608. View Abstract
  6. A Prospective Study of Parental Experience with Thickening Feeds for Children with Oropharyngeal Dysphagia and Gastroesophageal Reflux. J Pediatr. 2023 09; 260:113510. View Abstract
  7. Gastrointestinal factors associated with risk of bronchiectasis in children. Pediatr Pulmonol. 2023 03; 58(3):899-907. View Abstract
  8. A Prospective Study of Brief Resolved Unexplained Events: Risk Factors for Persistent Symptoms. Hosp Pediatr. 2022 12 01; 12(12):1030-1043. View Abstract
  9. Airway Impedance: A Novel Diagnostic Tool to Predict Extraesophageal Airway Inflammation. J Pediatr. 2023 05; 256:5-10.e2. View Abstract
  10. A prospective study of intrapyloric botulinum toxin and EndoFLIP in children with nausea and vomiting. Neurogastroenterol Motil. 2022 Nov; 34(11):e14428. View Abstract
  11. Gastrostomy Tube Use in Pediatrics: A Systematic Review. Pediatrics. 2022 06 01; 149(6). View Abstract
  12. Low diagnostic yield in BRUE hospitalization. J Pediatr. 2022 05; 244:250-254. View Abstract
  13. Pneumatosis intestinalis after thoracic organ transplantation in children: A case series and review of the literature. Clin Transplant. 2022 06; 36(6):e14654. View Abstract
  14. Assessing Sex, Gender Identity, Sexual Orientation, Race, Ethnicity, Socioeconomic Status, and Mental Health Concerns in Tobacco Use Disorder Treatment Research: Measurement Challenges and Recommendations From a Society for Research on Nicotine and Tobacco Pre-conference Workshop. Nicotine Tob Res. 2022 03 26; 24(5):643-653. View Abstract
  15. Effect of Added Free Water to Enteral Tube Feeds in Children Receiving Commercial Blends. J Pediatr Gastroenterol Nutr. 2022 03 01; 74(3):419-423. View Abstract
  16. International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. Clin Gastroenterol Hepatol. 2022 11; 20(11):2474-2484.e3. View Abstract
  17. The Utility of Functional Luminal Imaging Probes Measurements to Diagnose Dysmotility and Their Relationship to Impaired Bolus Clearance. J Pediatr Gastroenterol Nutr. 2022 04 01; 74(4):523-528. View Abstract
  18. Development of a Core Outcome Set for Children Aged 1-18 Years with Gastroesophageal Reflux Disease. J Pediatr. 2022 06; 245:129-134.e5. View Abstract
  19. Prucalopride for Treatment of Upper Gastrointestinal Symptoms in Children. Paediatr Drugs. 2022 Jan; 24(1):73-81. View Abstract
  20. Impact of Coronavirus Disease 2019 on the Pediatric Population with Aerodigestive Disease. J Pediatr. 2022 04; 243:14-20.e1. View Abstract
  21. Risk Factors for Bile Aspiration and its Impact on Clinical Outcomes. Clin Transl Gastroenterol. 2021 12 07; 12(12):e00434. View Abstract
  22. Overall Impact of Coronavirus Disease 2019 Outbreak in Children With Functional Abdominal Pain Disorders: Results From the First Pandemic Phase. J Pediatr Gastroenterol Nutr. 2021 12 01; 73(6):689-694. View Abstract
  23. A Retrospective Review of Primary Percutaneous Endoscopic Gastrostomy and Laparoscopic Gastrostomy Tube Placement. J Pediatr Gastroenterol Nutr. 2021 Nov 01; 73(5):586-591. View Abstract
  24. Evaluating the adherence to national guidelines for treatment of gastroesophageal reflux in infants. Acta Paediatr. 2022 Feb; 111(2):440-441. View Abstract
  25. Factors associated with past-year attempts to quit e-cigarettes among current users: Findings from the Population Assessment of Tobacco and Health Wave 4 (2017-2018). Drug Alcohol Depend. 2021 10 01; 227:108973. View Abstract
  26. Risk of aspiration pneumonia in paediatric patients with dysphagia who were found to have laryngeal penetration on the instrumental swallow evaluation: a systematic review protocol. BMJ Open. 2021 08 03; 11(8):e048422. View Abstract
  27. Pharmacogenomics fail to explain proton pump inhibitor refractory esophagitis in pediatric esophageal atresia. Neurogastroenterol Motil. 2022 01; 34(1):e14217. View Abstract
  28. PedsQL™ Gastroparesis Symptoms Module Domain and Item Development: Qualitative Methods. J Pediatr Gastroenterol Nutr. 2021 08 01; 73(2):192-196. View Abstract
  29. Gastro-oesophageal reflux disease. Nat Rev Dis Primers. 2021 07 29; 7(1):55. View Abstract
  30. Response to Febo-Rodriguez et al. Am J Gastroenterol. 2021 07 01; 116(7):1553. View Abstract
  31. Acid Suppression Does Not Improve Laryngomalacia Outcomes but Treatment for Oropharyngeal Dysphagia Might Be Protective. J Pediatr. 2021 Nov; 238:42-49.e2. View Abstract
  32. Metabolomic profiling of extraesophageal reflux disease in children. Clin Transl Sci. 2021 09; 14(5):2025-2033. View Abstract
  33. Overlapping Symptoms of Gastroesophageal Reflux and Aspiration Highlight the Limitations of Validated Questionnaires. J Pediatr Gastroenterol Nutr. 2021 03 01; 72(3):372-377. View Abstract
  34. Clinician Knowledge of Societal Guidelines on Management of Gastrointestinal Complications in Esophageal Atresia. J Pediatr Gastroenterol Nutr. 2021 02 01; 72(2):232-238. View Abstract
  35. Development of Entrustable Professional Activities and Standards in Training in Pediatric Neurogastroenterology and Motility: North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and American Neurogastroenterology and Motility Society Position Paper. J Pediatr Gastroenterol Nutr. 2021 01 01; 72(1):168-180. View Abstract
  36. Comparison of Aerodigestive and Nonaerodigestive Provider Responses to Clinical Case Vignettes. J Pediatr. 2021 05; 232:166-175.e2. View Abstract
  37. The impact of gastrointestinal dysmotility on the aerodigestive microbiome of pediatric lung transplant recipients. J Heart Lung Transplant. 2021 03; 40(3):210-219. View Abstract
  38. The Ethics of Feeding the Aspirating Child in an Age of Increasing Patient Complexity. J Pediatr Gastroenterol Nutr. 2020 11; 71(5):586-588. View Abstract
  39. Pediatric Solid Gastric Emptying Scintigraphy: Normative Value Guidelines and Nonstandard Meal Alternatives. Am J Gastroenterol. 2020 11; 115(11):1830-1839. View Abstract
  40. Prevalence of Feeding Disorders: A Tough Reality to Swallow. J Pediatr. 2021 01; 228:13-14. View Abstract
  41. A Pilot Randomized Clinical Trial of Brief Interventions to Encourage Quit Attempts in Smokers From Socioeconomic Disadvantage. Nicotine Tob Res. 2020 08 24; 22(9):1500-1508. View Abstract
  42. Proceedings of the 2018 Advances In Motility and In NeuroGastroenterology: AIMING for the Future Single Topic Symposium. J Pediatr Gastroenterol Nutr. 2020 08; 71(2):e59-e67. View Abstract
  43. GOT MILK-ish? J Pediatr Gastroenterol Nutr. 2020 08; 71(2):149. View Abstract
  44. Botulinum Toxin as a Treatment for Feeding Difficulties in Young Children. J Pediatr. 2020 11; 226:228-235. View Abstract
  45. Functional Luminal Imaging Probe Assessment in Postfundoplication Patients Changes Management Beyond Manometry. J Pediatr Gastroenterol Nutr. 2020 06; 70(6):e119-e123. View Abstract
  46. Viscosity of Commercial Food-based Formulas and Home-prepared Blenderized Feeds. J Pediatr Gastroenterol Nutr. 2020 06; 70(6):e124-e128. View Abstract
  47. Adherence to low-calorie and low-sugar diets is uniquely associated with distinct facets of appearance/weight-related smoking motivations. J Behav Med. 2020 06; 43(3):487-492. View Abstract
  48. Omeprazole inhibits IgE-mediated mast cell activation and allergic inflammation induced by ingested allergen in mice. J Allergy Clin Immunol. 2020 10; 146(4):884-893.e5. View Abstract
  49. Reply. J Pediatr. 2020 05; 220:268. View Abstract
  50. A Quality Improvement Initiative to Reduce Gastrostomy Tube Placement in Aspirating Patients. Pediatrics. 2020 02; 145(2). View Abstract
  51. Abnormal 24-hour pH-impedance Testing Does Not Predict Reduced Quality of Life in Children With Reflux Symptoms. J Pediatr Gastroenterol Nutr. 2020 01; 70(1):31-36. View Abstract
  52. Over the Counter Complexities. J Pediatr Gastroenterol Nutr. 2020 01; 70(1):1. View Abstract
  53. The Spectrum of Reflux Phenotypes. Gastroenterol Hepatol (N Y). 2019 Dec; 15(12):646-654. View Abstract
  54. Continuous Feedings Are Not Associated With Lower Rates of Gastroesophageal Reflux When Compared With Bolus Feedings. J Pediatr Gastroenterol Nutr. 2019 12; 69(6):678-681. View Abstract
  55. Pepsin Triggers Neutrophil Migration Across Acid Damaged Lung Epithelium. Sci Rep. 2019 09 24; 9(1):13778. View Abstract
  56. Deepening the Understanding of Functional and Motility Disorders. J Pediatr Gastroenterol Nutr. 2019 06; 68(6):761. View Abstract
  57. Health Outcomes and Quality of Life Indices of Children Receiving Blenderized Feeds via Enteral Tube. J Pediatr. 2019 08; 211:139-145.e1. View Abstract
  58. Aerodigestive sampling reveals altered microbial exchange between lung, oropharyngeal, and gastric microbiomes in children with impaired swallow function. PLoS One. 2019; 14(5):e0216453. View Abstract
  59. Clinical Aspects of Thickeners for Pediatric Gastroesophageal Reflux and Oropharyngeal Dysphagia. Curr Gastroenterol Rep. 2019 May 16; 21(7):30. View Abstract
  60. The Impact of the American Academy of Pediatrics Brief Resolved Unexplained Event Guidelines on Gastrointestinal Testing and Prescribing Practices. J Pediatr. 2019 08; 211:112-119.e4. View Abstract
  61. Development of a Core Outcome Set for Infant Gastroesophageal Reflux Disease. J Pediatr Gastroenterol Nutr. 2019 05; 68(5):655-661. View Abstract
  62. Size and Prevalence of Pediatric Aerodigestive Programs in 2017. J Pediatr Gastroenterol Nutr. 2019 05; 68(5):e72-e76. View Abstract
  63. Gastrointestinal Dysmotility and the Implications for Respiratory Disease. Curr Treat Options Pediatr. 2019 Jun; 5(2):197-214. View Abstract
  64. Feeding Interventions Are Associated With Improved Outcomes in Children With Laryngeal Penetration. J Pediatr Gastroenterol Nutr. 2019 02; 68(2):218-224. View Abstract
  65. Association of Proton Pump Inhibitors With Hospitalization Risk in Children With Oropharyngeal Dysphagia. JAMA Otolaryngol Head Neck Surg. 2018 12 01; 144(12):1116-1124. View Abstract
  66. A Distinct Esophageal mRNA Pattern Identifies Eosinophilic Esophagitis Patients With Food Impactions. Front Immunol. 2018; 9:2059. View Abstract
  67. Respiratory symptoms associated with eosinophilic esophagitis. Pediatr Pulmonol. 2018 11; 53(11):1587-1591. View Abstract
  68. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018 10; 155(4):1022-1033.e10. View Abstract
  69. Proton Pump Inhibitor Use and Outcomes in Children With Respiratory Symptoms. JAMA Otolaryngol Head Neck Surg. 2018 07 01; 144(7):555-556. View Abstract
  70. Presenting Signs and Symptoms do not Predict Aspiration Risk in Children. J Pediatr. 2018 10; 201:141-146. View Abstract
  71. Preoperative Evaluation Is Not Predictive of Transpyloric Feeding Conversion in Gastrostomy-dependent Pediatric Patients. J Pediatr Gastroenterol Nutr. 2018 Jun; 66(6):887-892. View Abstract
  72. Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2018 03; 66(3):516-554. View Abstract
  73. The Case for Thoughtful Prescribing of Proton Pump Inhibitors in Infants. J Pediatr Gastroenterol Nutr. 2018 01; 66(1):e26-e27. View Abstract
  74. Novel Pressure-Impedance Parameters for Evaluating Esophageal Function in Pediatric Achalasia. J Pediatr Gastroenterol Nutr. 2018 01; 66(1):37-42. View Abstract
  75. How to Care for Patients with EA-TEF: The Known and the Unknown. Curr Gastroenterol Rep. 2017 Nov 25; 19(12):65. View Abstract
  76. Oropharyngeal Dysphagia Is Strongly Correlated With Apparent Life-Threatening Events. J Pediatr Gastroenterol Nutr. 2017 08; 65(2):168-172. View Abstract
  77. The Prevalence of Rome IV Nonerosive Esophageal Phenotypes in Children. J Pediatr. 2017 10; 189:86-91. View Abstract
  78. Feeding Problems and Their Underlying Mechanisms in the Esophageal Atresia-Tracheoesophageal Fistula Patient. Front Pediatr. 2017; 5:127. View Abstract
  79. Impact of gastroesophageal reflux and delayed gastric emptying on pediatric lung transplant outcomes. J Heart Lung Transplant. 2017 Aug; 36(8):854-861. View Abstract
  80. The Edematous and Erythematous Airway Does Not Denote Pathologic Gastroesophageal Reflux. J Pediatr. 2017 04; 183:127-131. View Abstract
  81. ESPGHAN-NASPGHAN Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Esophageal Atresia-Tracheoesophageal Fistula. J Pediatr Gastroenterol Nutr. 2016 11; 63(5):550-570. View Abstract
  82. Gastroesophageal Reflux Burden, Even in Children That Aspirate, Does Not Increase Pediatric Hospitalization. J Pediatr Gastroenterol Nutr. 2016 08; 63(2):210-7. View Abstract
  83. Salivary Pepsin Lacks Sensitivity as a Diagnostic Tool to Evaluate Extraesophageal Reflux Disease. J Pediatr. 2016 10; 177:53-58. View Abstract
  84. Airway reflux. Ann N Y Acad Sci. 2016 10; 1381(1):5-13. View Abstract
  85. Symptom Association: An Imperfect Pairing. J Pediatr Gastroenterol Nutr. 2016 Apr; 62(4):517-8. View Abstract
  86. Acid Rather Than Nonacid Reflux Burden Is a Predictor of Tooth Erosion. J Pediatr Gastroenterol Nutr. 2016 Feb; 62(2):309-13. View Abstract
  87. Oral Feeding Reduces Hospitalizations Compared with Gastrostomy Feeding in Infants and Children Who Aspirate. J Pediatr. 2016 Mar; 170:79-84. View Abstract
  88. Feeding Difficulties in Children with Esophageal Atresia. Paediatr Respir Rev. 2016 Jun; 19:21-7. View Abstract
  89. 16S community profiling identifies proton pump inhibitor related differences in gastric, lung, and oropharyngeal microflora. J Pediatr. 2015 Apr; 166(4):917-23. View Abstract
  90. Changes in gastric and lung microflora with acid suppression: acid suppression and bacterial growth. JAMA Pediatr. 2014 Oct; 168(10):932-7. View Abstract
  91. The sensitivity of acoustic cough recording relative to intraesophageal pressure recording and patient report during reflux testing. Neurogastroenterol Motil. 2014 Nov; 26(11):1635-41. View Abstract
  92. Gastroesophageal reflux in infants: more than just a pHenomenon. JAMA Pediatr. 2014 Jan; 168(1):83-9. View Abstract
  93. Intraesophageal pressure recording improves the detection of cough during multichannel intraluminal impedance testing in children. J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):22-6. View Abstract
  94. The utility of endoscopy and multichannel intraluminal impedance testing in children with cough and wheezing. Pediatr Pulmonol. 2014 Nov; 49(11):1090-6. View Abstract
  95. Endoscopic intrapyloric injection of botulinum toxin A in the treatment of children with gastroparesis: a retrospective, open-label study. Gastrointest Endosc. 2012 Feb; 75(2):302-9. View Abstract
  96. The impact of reflux burden on Pseudomonas positivity in children with cystic fibrosis. Pediatr Pulmonol. 2012 Jun; 47(6):582-7. View Abstract
  97. The presence of pepsin in the lung and its relationship to pathologic gastro-esophageal reflux. Neurogastroenterol Motil. 2012 Feb; 24(2):129-33, e84-5. View Abstract
  98. Anorectal manometry may identify children with spinal cord lesions. J Pediatr Gastroenterol Nutr. 2011 Nov; 53(5):507-11. View Abstract
  99. Interobserver and intraobserver variability in pH-impedance analysis between 10 experts and automated analysis. J Pediatr. 2012 Mar; 160(3):441-446.e1. View Abstract
  100. Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders. J Pediatr. 2011 Sep; 159(3):504-6. View Abstract
  101. Incidence of gastroesophageal reflux during transpyloric feeds. J Pediatr Gastroenterol Nutr. 2011 May; 52(5):532-5. View Abstract
  102. Does reflux monitoring with multichannel intraluminal impedance change clinical decision making? J Pediatr Gastroenterol Nutr. 2011 Apr; 52(4):404-7. View Abstract
  103. Effect of different pH criteria on dual-sensor pH monitoring in the evaluation of supraesophageal gastric reflux in children. J Pediatr Gastroenterol Nutr. 2011 Apr; 52(4):399-403. View Abstract
  104. Esophageal impedance monitoring for gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):129-39. View Abstract
  105. Reflux events detected by pH-MII do not determine fundoplication outcome. J Pediatr Gastroenterol Nutr. 2010 Mar; 50(3):251-5. View Abstract
  106. Esophageal dysmotility in children with eosinophilic esophagitis: a study using prolonged esophageal manometry. Am J Gastroenterol. 2009 Dec; 104(12):3050-7. View Abstract
  107. Endoscopic repair of laryngeal cleft type I and type II: when and why? Laryngoscope. 2009 Sep; 119(9):1797-802. View Abstract
  108. Role of acid and nonacid reflux in children with eosinophilic esophagitis compared with patients with gastroesophageal reflux and control patients. J Pediatr Gastroenterol Nutr. 2008 May; 46(5):520-3. View Abstract
  109. Lipid-laden macrophage index is not an indicator of gastroesophageal reflux-related respiratory disease in children. Pediatrics. 2008 Apr; 121(4):e879-84. View Abstract
  110. Esophageal dysmotility in patients who have eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2008 Jan; 18(1):73-89; ix. View Abstract
  111. The sensitivity of multichannel intraluminal impedance and the pH probe in the evaluation of gastroesophageal reflux in children. Clin Gastroenterol Hepatol. 2006 Feb; 4(2):167-72. View Abstract
  112. Use of multi-channel intraluminal impedance (MII) in the evaluation of children with respiratory symptoms: a new phenomenon? J Pediatr Gastroenterol Nutr. 2005 Aug; 41(2):166-8. View Abstract
  113. The importance of multichannel intraluminal impedance in the evaluation of children with persistent respiratory symptoms. Am J Gastroenterol. 2004 Dec; 99(12):2452-8. View Abstract
  114. Incidence of spinal cord lesions in patients with intractable constipation. J Pediatr. 2004 Sep; 145(3):409-11. View Abstract
  115. Impeding gastroesophageal refluxate: a new application of an old medication. Gastroenterology. 2003 Sep; 125(3):984-5; discussion 985-6. View Abstract
  116. Severe pancytopenia from thiopurine methyltransferase deficiency: a preventable complication of 6-mercaptopurine therapy in children with Crohn disease. J Pediatr Gastroenterol Nutr. 2002 Nov; 35(5):695-9. View Abstract

Contact Rachel Rosen

Print Profile