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Research Overview

Stephanie Jo Brewster is a board-certified and licensed genetic counselor with over 25 years of clinical research experience. She has a longstanding interest in the ethical issues surrounding genetic and translational research and its impact on participating families. In her current and previous positions, Ms. Brewster has implemented and overseen numerous pediatric studies and clinical trials providing guidance on protocol and consent form development, IRB facilitation, infrastructure creation and study staff supervision. She has acted as a consultant to biotech companies conducting clinical research, has served on numerous committees of the National Society of Genetic Counselors and served for 12 years on the Boston University School of Medicine Genetic Counseling Program Advisory Board. Ms. Brewster is a current member of the Boston Children's Institutional Review Board and its EDI subcommittee. She is also a strategic advisor to the Developmental Medicine-Clinical Research Laboratories (DM-CRL).

Research Background

Ms. Brewster received her Bachelor of Science degree in Biology from Syracuse University and her Master of Science degree in Human Genetics from Sarah Lawrence College. Ms. Brewster is board certified by the American Board of Genetic Counseling and licensed by the Massachusetts Genetic Counseling Board of Registration.

Selected Publications

  1. Harstad E, Golden M, Sideridis G, Brewster S, and Barbaresi W. Developmental and Psychiatric Conditions Among 5–7 Year Old Children with Non persistent and Persistent Autism. Autism Dev Disord. [2]https://doi.org/10.1007/s10803-024-06628-4, 2024.
  2. Arnett A, Harstad E, O’Connell M, Hayes K, Brewster S, Barbaresi W and Doan R. Rare De Novo and Inherited Genes in Familial and Nonfamilial Pediatric Attention-Deficit/Hyperactivity Disorder. JAMA Pediatr. 178(1):81-84, 2024.
  3. Harstad E, Hanson E, Brewster S, DePillis R, Milliken A, Aberbach G, Sideridis G and Barbaresi W. Persistence of Autism Spectrum Disorder From Early Childhood Through School Age. JAMA Pediatr. 177(11):1197-1205, 2023.
  4. Chopra C, Modi M, Dies K, Chamberlin N, Buttermore E, Brewster S, Prock L, and Sahin M. GENE TARGET: A framework for evaluating Mendelian neurodevelopmental disorders for gene therapy. Mol Ther Methods Clin Dev. 27: 32-46, 2022.
  5. Bridgemohan C, Cochran DM, Howe YJ, Pawlowski K, Zimmerman AW, Anderson GM, Choueiri R, Sices L, Miller KJ, Ultmann M, Helt J, Forbes PW, Farfel L, Brewster SJ, Frazier JA and Neumeyer AM on behalf of the Autism Consortium Biomarkers Study Clinicians. Investigating Potential Biomarkers in Autism Spectrum Disorder. Front. Integr. Neurosci. 13 (31):1-11, 2019.
  6. Brewster SJ, Jacobsen C, Shen Y and Holm IA, “Genetic Testing and Counseling”, in Thakker RV, Whyte MP, Eisman JA and Igarashi T, Eds., Genetics of Bone Biology and Skeletal Disease (Elsevier Inc., 2nd Edition), pp. 159-169, 2017.
  7. Sices L, Pawlowski K, Farfel L, Phillips D, Howe Y, Cochran DM, Choueiri R, Forbes PW, Brewster SJ, Frazier JA, Neumeyer A, Bridgemohan C. Feasibility of Conducting Autism Biomarker Research in the Clinical Setting. J Dev Behav Pediatr. 38(7):483-492, 2017.
  8. Field T, Brewster SJ, Towne M, and Campion MW. Emerging Genetic Counselor Roles within the Biotechnology and Pharmaceutical Industries: as Industry Interest Grows in Rare Genetic Disorders, How are Genetic Counselors Joining the Discussion?. Journal of Genetic Counseling. 25(4):708-19, 2016.
  9. Holm IA, Savage SK, Green RC, Juengst E, McGuire A, Kornetsky S, Brewster SJ, Joffe S and Taylor P. Guidelines for return of research results from pediatric genomic studies: deliberations of the Boston Children’s Hospital Gene Partnership Informed Cohort Oversight Board. Genetics in Medicine. 16: 547-552, 2014.
  10. Shen Y, Dies KA, Holm IA, Bridgemohan C, Sobeih M, Caronna EB, Miller KJ, Frazier JA, Silverstein I, Picker J, Weissman L, Raffalli P, Jeste S, Demmer LA, Peters HK, Brewster SJ, Kowalczyk SJ, Rosen-Sheidley B, McGowan C, Duda AW, Lincoln SA, Lowe KR, Schonwald A, Robbins M, Hisama F, Wolff R, Becker R, Nasir R, Urion DK, Milunsky JM, Rappaport L, Gusella JF,Walsh CA, Wu BL, Miller DT and on behalf of the Autism Consortium Clinical Genetics/DNA Diagnostics Collaboration. Clinical Genetic Testing for Patients with Autism Spectrum Disorders. Pediatrics. 125(4): 727-735, 2010.