Current Environment:

Summary

The primary objective of this investigation is to evaluate the feasibility and safety of implantable loop recorder implantation (using the LUX-DX™) in newborns undergoing stage 1 palliation. The secondary objective of the investigation is to evaluate the feasibility of continuous measurement of heart rate and arrhythmia using an implantable loop recorder (LUX-Dx™) during the interstage period. An implantable loop recorder will be placed at the time of chest closure following stage 1 palliation (either at the time of index surgery or delayed). The device will be placed in a subclavicular pouch through the existing sternotomy incision. Participants will be in the study for 6 months to 3 years.

Conditions

Univentricular Heart

Recruitment Status

RECRUITING

Eligibility Criteria

Inclusion Criteria:

* Patients with single ventricle physiology undergoing stage 1 palliation in the 1st month of life

Exclusion Criteria:

* Prematurity (\<36 weeks gestational age)
* Birth weight \<2.5 kg
* Hybrid stage 1 palliation (patent ductus arteriosus stenting, bilateral pulmonary artery bands)
* Presence and/or need for devices sensitive to magnetic fields such as hearing aids, pacemaker, and other implanted devices.
* Clinical team does not think that the patient is a good candidate

Intervention

Intervention Type

Intervention Name

DEVICE

LUX-Dx™

Phase

EARLY_PHASE1

Gender

ALL

Min Age

N/A

Max Age

30 Days

Download Date

2024-02-07

Principal Investigator

This field has been modified from ClinicalTrials.gov to show a contact specific to Boston Children's.

Primary Contact Information

Olivia Rossi
olivia.rossi@cardio.chboston.org

This field has been modified from ClinicalTrials.gov to show a contact specific to Boston Children's.

For more information on this trial, visit clinicaltrials.gov.

Contact

For more information and to contact the study team:

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study NCT05744934 Olivia Rossi olivia.rossi@cardio.chboston.org