Basic Research Labs | Overview
The Hansen Laboratory studies the role of Ras-like GTP-binding proteins in epithelial morphogenesis and oncogenic transformation.
The Kagan Laboratory is focused on understanding the regulation of innate immunity at the level of microbial detection and signal transduction. Of particular interest is the family of Toll-like receptors (TLRs), which evolved to specifically link microbial detection to the control of adaptive immunity.
The Lencer Laboratory and four NIH-funded core laboratories form a consortium of scientists focused on gastrointestinal research.
The Naqvi Laboratory uses quantitative approaches to understand transcriptional control during human development and how its disruption leads to disease, with a focus on neural crest cells and corresponding disorders of the enteric nervous system.
The Ordovas-Montanes Laboratory seeks to understand the principles of how inflammation drives memory formation in human barrier tissues in order to program and re-program them in human disease.
The Rao Laboratory seeks to understand how the intrinsic nerve circuits of the gastrointestinal tract normally regulate digestive health, and how dysfunction in these circuits leads to digestive disease.
The Snapper Laboratory is part of a larger consortium of talented interdisciplinary investigators that focuses on gastrointestinal research.
The Thiagarajah Laboratory aims to understand how cells sense and interact with their surroundings and how membrane proteins contribute to immune function, host-microbial symbiosis, and cellular metabolism.
The Zhou Laboratory applies interdisciplinary approaches to understand how immune cells interact and communicate with their neighbors and surrounding environment.