Current Environment: Production

Jocelyn Silvester | Medical Services

Specialties

Programs & Services

Languages

  • English

Jocelyn Silvester | Education

Medical School

Dalhousie University , 2008 , Halifax , Nova Scotia, Canada

Dalhousie University

2008, Halifax, Nova Scotia, Canada

Residency

University of Manitoba

2012, Winnipeg, Manitoba, Canada

Fellowship

Boston Children's Hospital

2016, Boston, MA

Jocelyn Silvester | Certifications

  • American Board of Pediatrics (Gastroenterology)
  • American Board of Pediatrics (General)

Jocelyn Silvester | Professional History

Dr. Silvester completed her PhD in Biology at the University of Cambridge, Cambridge, England, prior to studying medicine at Dalhousie University in Halifax, Nova Scotia, Canada. She completed her residency at the University of Manitoba in Winnipeg, Canada and her Fellowship in Gastroenterology, Hepatology and Nutrition at Boston Children’s Hospital. Dr. Silvester continues to work as a general pediatrician in remote regions of Northern Canada as well as at Boston Children’s Hospital. Her research interests include the diagnosis and management of celiac disease.

Jocelyn Silvester | Publications

  1. Identifying parentally perceived barriers for children with celiac disease to participate in elementary school meal programs. JPGN Rep. 2024 Nov; 5(4):470-474. View Identifying parentally perceived barriers for children with celiac disease to participate in elementary school meal programs. Abstract

  2. Effect of Adopting a Gluten-Free Diet on Exposure to Arsenic and Other Heavy Metals in Children With Celiac Disease: A Prospective Cohort Study. Am J Gastroenterol. 2024 Oct 09. View Effect of Adopting a Gluten-Free Diet on Exposure to Arsenic and Other Heavy Metals in Children With Celiac Disease: A Prospective Cohort Study. Abstract

  3. ViCE: An automated and quantitative program to assess intestinal tissue morphology. J Pathol Inform. 2024 Dec; 15:100397. View ViCE: An automated and quantitative program to assess intestinal tissue morphology. Abstract

  4. Clinical presentation and factors associated with gluten exposure in children with celiac disease. J Pediatr Gastroenterol Nutr. 2024 Oct; 79(4):895-904. View Clinical presentation and factors associated with gluten exposure in children with celiac disease. Abstract

  5. Finding the sweet spot: Diagnosing celiac disease in children with type 1 diabetes. J Pediatr Gastroenterol Nutr. 2024 Sep; 79(3):449-450. View Finding the sweet spot: Diagnosing celiac disease in children with type 1 diabetes. Abstract

  6. HLA-DQ7 haplotype among individuals with suspected celiac disease. Dig Liver Dis. 2024 Aug; 56(8):1414-1416. View HLA-DQ7 haplotype among individuals with suspected celiac disease. Abstract

  7. Celiac disease in North America: What is the current practice of pediatric gastroenterology providers? JPGN Rep. 2024 Aug; 5(3):276-283. View Celiac disease in North America: What is the current practice of pediatric gastroenterology providers? Abstract

  8. Adapting celiac immunity for the future: Addressing the immunization gap in children with celiac disease. J Pediatr Gastroenterol Nutr. 2024 Aug; 79(2):195-197. View Adapting celiac immunity for the future: Addressing the immunization gap in children with celiac disease. Abstract

  9. Past, Present, and Future of Noninvasive Tests to Assess Gluten Exposure, Celiac Disease Activity, and End-Organ Damage. Gastroenterology. 2024 Jun; 167(1):159-171. View Past, Present, and Future of Noninvasive Tests to Assess Gluten Exposure, Celiac Disease Activity, and End-Organ Damage. Abstract

  10. A tip-predominant distribution of villous intraepithelial lymphocytes is not specific to celiac disease in children with Marsh I lesions. Am J Clin Pathol. 2024 Feb 01; 161(2):149-154. View A tip-predominant distribution of villous intraepithelial lymphocytes is not specific to celiac disease in children with Marsh I lesions. Abstract

  11. Anti-infliximab antibodies and low infliximab levels correlate with drug discontinuation in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2024 Feb; 78(2):261-271. View Anti-infliximab antibodies and low infliximab levels correlate with drug discontinuation in pediatric inflammatory bowel disease. Abstract

  12. A Composite Morphometric Duodenal Biopsy Mucosal Scale for Celiac Disease Encompassing Both Morphology and Inflammation. Clin Gastroenterol Hepatol. 2024 Jun; 22(6):1238-1244.e3. View A Composite Morphometric Duodenal Biopsy Mucosal Scale for Celiac Disease Encompassing Both Morphology and Inflammation. Abstract

  13. Comparing Gastrointestinal Endoscopy Findings in Children with Autism, Developmental Delay, or Typical Development. J Pediatr. 2024 Jan; 264:113737. View Comparing Gastrointestinal Endoscopy Findings in Children with Autism, Developmental Delay, or Typical Development. Abstract

  14. Standardizing Randomized Controlled Trials in Celiac Disease: An International Multidisciplinary Appropriateness Study. Gastroenterology. 2024 01; 166(1):88-102. View Standardizing Randomized Controlled Trials in Celiac Disease: An International Multidisciplinary Appropriateness Study. Abstract

  15. A Clinician's Guide to Gluten Challenge. J Pediatr Gastroenterol Nutr. 2023 12 01; 77(6):698-702. View A Clinician's Guide to Gluten Challenge. Abstract

  16. Letter to the Editor in Response to ACG Guidelines Update: Diagnosis and Management of Celiac Disease. Am J Gastroenterol. 2023 11 01; 118(11):2094-2095. View Letter to the Editor in Response to ACG Guidelines Update: Diagnosis and Management of Celiac Disease. Abstract

  17. Low Levels of Detectable Urine and Stool GIPs in Children with Celiac Disease on a Gluten-Free Diet. JPGN Rep. 2023 Aug; 4(3):e323. View Low Levels of Detectable Urine and Stool GIPs in Children with Celiac Disease on a Gluten-Free Diet. Abstract

  18. The Spectrum of Duodenal Histologic Findings in Patients With Trisomy 21: A Multicenter Study. J Pediatr Gastroenterol Nutr. 2023 08 01; 77(2):184-190. View The Spectrum of Duodenal Histologic Findings in Patients With Trisomy 21: A Multicenter Study. Abstract

  19. Pancreatic enzyme supplementation versus placebo for improvement of gastrointestinal symptoms in non-responsive celiac disease: A cross-over randomized controlled trial. Front Med (Lausanne). 2022; 9:1001879. View Pancreatic enzyme supplementation versus placebo for improvement of gastrointestinal symptoms in non-responsive celiac disease: A cross-over randomized controlled trial. Abstract

  20. Editorial: Best supporting actors: shining a light on the diverse roles of immune cells in gastrointestinal disease. Curr Opin Gastroenterol. 2022 11 01; 38(6):533-534. View Editorial: Best supporting actors: shining a light on the diverse roles of immune cells in gastrointestinal disease. Abstract

  21. Review article: Becoming and being coeliac-special considerations for childhood, adolescence and beyond. Aliment Pharmacol Ther. 2022 07; 56 Suppl 1:S73-S85. View Review article: Becoming and being coeliac-special considerations for childhood, adolescence and beyond. Abstract

  22. Dating While Gluten-Free-Don't Kiss and Don't Tell? Dig Dis Sci. 2022 11; 67(11):4976-4978. View Dating While Gluten-Free-Don't Kiss and Don't Tell? Abstract

  23. Survey-Based Study on Food Insecurity During COVID-19 for Households With Children on a Prescribed Gluten-Free Diet. Am J Gastroenterol. 2022 06 01; 117(6):931-934. View Survey-Based Study on Food Insecurity During COVID-19 for Households With Children on a Prescribed Gluten-Free Diet. Abstract

  24. Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome. Front Psychiatry. 2022; 13:842030. View Genotypes of Pain and Analgesia in a Randomized Trial of Irritable Bowel Syndrome. Abstract

  25. Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome. Front Pain Res (Lausanne). 2021; 2:775386. View Genomic Effects Associated With Response to Placebo Treatment in a Randomized Trial of Irritable Bowel Syndrome. Abstract

  26. Prevalence of celiac disease in China: Meta-analysis and serological survey in high-risk populations. J Dig Dis. 2021 Nov; 22(11):645-655. View Prevalence of celiac disease in China: Meta-analysis and serological survey in high-risk populations. Abstract

  27. Editorial: No organ is an island: the role of gut-organ axes in human health and disease. Curr Opin Gastroenterol. 2021 11 01; 37(6):545-546. View Editorial: No organ is an island: the role of gut-organ axes in human health and disease. Abstract

  28. Society for the Study of Celiac Disease position statement on gaps and opportunities in coeliac disease. Nat Rev Gastroenterol Hepatol. 2021 12; 18(12):875-884. View Society for the Study of Celiac Disease position statement on gaps and opportunities in coeliac disease. Abstract

  29. Clinical classification and long-term outcomes of seronegative coeliac disease: a 20-year multicentre follow-up study. Aliment Pharmacol Ther. 2021 11; 54(10):1278-1289. View Clinical classification and long-term outcomes of seronegative coeliac disease: a 20-year multicentre follow-up study. Abstract

  30. Patient Perspectives on the Long-term Management of Celiac Disease. J Clin Gastroenterol. 2022 Nov-Dec 01; 56(10):869-874. View Patient Perspectives on the Long-term Management of Celiac Disease. Abstract

  31. Celiac Disease: Fallacies and Facts. Am J Gastroenterol. 2021 06 01; 116(6):1148-1155. View Celiac Disease: Fallacies and Facts. Abstract

  32. Non-responsive celiac disease in children on a gluten free diet. World J Gastroenterol. 2021 Apr 07; 27(13):1311-1320. View Non-responsive celiac disease in children on a gluten free diet. Abstract

  33. Editorial: Advances in Gastrointestinal Immunology. Curr Opin Gastroenterol. 2020 11; 36(6):463. View Editorial: Advances in Gastrointestinal Immunology. Abstract

  34. Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial. Gastroenterology. 2021 02; 160(3):720-733.e8. View Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial. Abstract

  35. Safety of a GFD in Pregnant Women Without Celiac Disease: Investigating Ingrained Habits. Dig Dis Sci. 2020 10; 65(10):2751-2753. View Safety of a GFD in Pregnant Women Without Celiac Disease: Investigating Ingrained Habits. Abstract

  36. The Gluten-Free Family Ripple Effect: The Tides that Bond and the Tides that Divide. Dig Dis Sci. 2020 10; 65(10):2754-2755. View The Gluten-Free Family Ripple Effect: The Tides that Bond and the Tides that Divide. Abstract

  37. Exposure sources, amounts and time course of gluten ingestion and excretion in patients with coeliac disease on a gluten-free diet. Aliment Pharmacol Ther. 2020 11; 52(9):1469-1479. View Exposure sources, amounts and time course of gluten ingestion and excretion in patients with coeliac disease on a gluten-free diet. Abstract

  38. Reply. Gastroenterology. 2020 09; 159(3):1189-1190. View Reply. Abstract

  39. Enteric-Release Budesonide May Be Useful in the Management of Non-Responsive Celiac Disease. Dig Dis Sci. 2021 06; 66(6):1989-1997. View Enteric-Release Budesonide May Be Useful in the Management of Non-Responsive Celiac Disease. Abstract

  40. The Utility of IgA-Based Serologic Markers in Diagnosing Celiac Disease in Children 24 Months of Age or Younger. J Pediatr. 2020 09; 224:158-161.e2. View The Utility of IgA-Based Serologic Markers in Diagnosing Celiac Disease in Children 24 Months of Age or Younger. Abstract

  41. Development of the Dietitian Integrated Evaluation Tool for Gluten-free Diets (DIET-GFD). Nutrition. 2020 10; 78:110819. View Development of the Dietitian Integrated Evaluation Tool for Gluten-free Diets (DIET-GFD). Abstract

  42. A Quantitative Assessment of Gluten Cross-contact in the School Environment for Children With Celiac Disease. J Pediatr Gastroenterol Nutr. 2020 03; 70(3):289-294. View A Quantitative Assessment of Gluten Cross-contact in the School Environment for Children With Celiac Disease. Abstract

  43. Can individuals with celiac disease identify gluten-free foods correctly? Clin Nutr ESPEN. 2020 04; 36:82-90. View Can individuals with celiac disease identify gluten-free foods correctly? Abstract

  44. Assessing the association between dipeptidyl peptidase-4 inhibitors use and celiac disease through drug adverse event reporting. Ther Adv Chronic Dis. 2020; 11:2040622320904301. View Assessing the association between dipeptidyl peptidase-4 inhibitors use and celiac disease through drug adverse event reporting. Abstract

  45. Celiac Disease: Extraintestinal Manifestations and Associated Conditions. J Clin Gastroenterol. 2020 01; 54(1):8-21. View Celiac Disease: Extraintestinal Manifestations and Associated Conditions. Abstract

  46. Most Patients With Celiac Disease on Gluten-Free Diets Consume Measurable Amounts of Gluten. Gastroenterology. 2020 04; 158(5):1497-1499.e1. View Most Patients With Celiac Disease on Gluten-Free Diets Consume Measurable Amounts of Gluten. Abstract

  47. Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease. PLoS One. 2019; 14(10):e0222952. View Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel disease. Abstract

  48. Preparation of Gluten-Free Foods Alongside Gluten-Containing Food May Not Always Be as Risky for Celiac Patients as Diet Guides Suggest. Gastroenterology. 2020 01; 158(1):273-275. View Preparation of Gluten-Free Foods Alongside Gluten-Containing Food May Not Always Be as Risky for Celiac Patients as Diet Guides Suggest. Abstract

  49. Inter- and Intra-assay Variation in the Diagnostic Performance of Assays for Anti-tissue Transglutaminase in 2 Populations. Clin Gastroenterol Hepatol. 2020 10; 18(11):2628-2630. View Inter- and Intra-assay Variation in the Diagnostic Performance of Assays for Anti-tissue Transglutaminase in 2 Populations. Abstract

  50. Can We Ignore the Utility of Deamidated Gliadin Peptide in the Diagnosis of Celiac Disease in Children? J Pediatr Gastroenterol Nutr. 2019 07; 69(1):e23. View Can We Ignore the Utility of Deamidated Gliadin Peptide in the Diagnosis of Celiac Disease in Children? Abstract

  51. Prospective longitudinal study: use of faecal gluten immunogenic peptides to monitor children diagnosed with coeliac disease during transition to a gluten-free diet. Aliment Pharmacol Ther. 2019 06; 49(12):1484-1492. View Prospective longitudinal study: use of faecal gluten immunogenic peptides to monitor children diagnosed with coeliac disease during transition to a gluten-free diet. Abstract

  52. Efficacy of Enteric-Release Oral Budesonide in Treatment of Acute Reactions to Gluten in Patients With Celiac Disease. Clin Gastroenterol Hepatol. 2020 01; 18(1):254-256. View Efficacy of Enteric-Release Oral Budesonide in Treatment of Acute Reactions to Gluten in Patients With Celiac Disease. Abstract

  53. Sequence of acquisition of self-management skills to follow a gluten-free diet by adults with celiac disease. Dig Liver Dis. 2019 08; 51(8):1096-1100. View Sequence of acquisition of self-management skills to follow a gluten-free diet by adults with celiac disease. Abstract

  54. Red Spot Lesions in the Duodenal Bulb Are a Highly Specific Endoscopic Sign of Celiac Disease: A Prospective Study. J Pediatr Gastroenterol Nutr. 2019 02; 68(2):251-255. View Red Spot Lesions in the Duodenal Bulb Are a Highly Specific Endoscopic Sign of Celiac Disease: A Prospective Study. Abstract

  55. Serum zonulin is elevated in IBS and correlates with stool frequency in IBS-D. United European Gastroenterol J. 2019 06; 7(5):709-715. View Serum zonulin is elevated in IBS and correlates with stool frequency in IBS-D. Abstract

  56. Lack of Follow-up of Pediatric Patients With Celiac Disease. Clin Gastroenterol Hepatol. 2019 11; 17(12):2603-2604. View Lack of Follow-up of Pediatric Patients With Celiac Disease. Abstract

  57. (Outcome) Measure for (Intervention) Measures: A Guide to Choosing the Appropriate Noninvasive Clinical Outcome Measure for Intervention Studies in Celiac Disease. Gastroenterol Clin North Am. 2019 03; 48(1):85-99. View (Outcome) Measure for (Intervention) Measures: A Guide to Choosing the Appropriate Noninvasive Clinical Outcome Measure for Intervention Studies in Celiac Disease. Abstract

  58. Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1570-E1577. View Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer. Abstract

  59. Symptoms of Functional Intestinal Disorders Are Common in Patients with Celiac Disease Following Transition to a Gluten-Free Diet. Dig Dis Sci. 2017 09; 62(9):2449-2454. View Symptoms of Functional Intestinal Disorders Are Common in Patients with Celiac Disease Following Transition to a Gluten-Free Diet. Abstract

  60. Tests for Serum Transglutaminase and Endomysial Antibodies Do Not Detect Most Patients With Celiac Disease and Persistent Villous Atrophy on Gluten-free Diets: a Meta-analysis. Gastroenterology. 2017 09; 153(3):689-701.e1. View Tests for Serum Transglutaminase and Endomysial Antibodies Do Not Detect Most Patients With Celiac Disease and Persistent Villous Atrophy on Gluten-free Diets: a Meta-analysis. Abstract

  61. Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 02; 64(2):286-291. View Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. Abstract

  62. Is Autoimmunity Infectious? The Effect of Gastrointestinal Viral Infections and Vaccination on Risk of Celiac Disease Autoimmunity. Clin Gastroenterol Hepatol. 2017 05; 15(5):703-705. View Is Autoimmunity Infectious? The Effect of Gastrointestinal Viral Infections and Vaccination on Risk of Celiac Disease Autoimmunity. Abstract

  63. Information seeking and anxiety among colonoscopy-naïve adults: Direct-to-colonoscopy vs traditional consult-first pathways. World J Gastrointest Endosc. 2016 Nov 16; 8(19):701-708. View Information seeking and anxiety among colonoscopy-naïve adults: Direct-to-colonoscopy vs traditional consult-first pathways. Abstract

  64. Symptomatic suspected gluten exposure is common among patients with coeliac disease on a gluten-free diet. Aliment Pharmacol Ther. 2016 09; 44(6):612-9. View Symptomatic suspected gluten exposure is common among patients with coeliac disease on a gluten-free diet. Abstract

  65. Is it gluten-free? Relationship between self-reported gluten-free diet adherence and knowledge of gluten content of foods. Nutrition. 2016 Jul-Aug; 32(7-8):777-83. View Is it gluten-free? Relationship between self-reported gluten-free diet adherence and knowledge of gluten content of foods. Abstract

  66. The Potential for Treatment of Potential Celiac Disease. Clin Gastroenterol Hepatol. 2016 May; 14(5):694-5. View The Potential for Treatment of Potential Celiac Disease. Abstract

  67. Recent Advances in Celiac Disease from TTG to Gluten in Pee. Clin Transl Gastroenterol. 2015 Nov 12; 6:e125. View Recent Advances in Celiac Disease from TTG to Gluten in Pee. Abstract

  68. Living gluten-free: adherence, knowledge, lifestyle adaptations and feelings towards a gluten-free diet. J Hum Nutr Diet. 2016 Jun; 29(3):374-82. View Living gluten-free: adherence, knowledge, lifestyle adaptations and feelings towards a gluten-free diet. Abstract

  69. Five things to know about...celiac disease. CMAJ. 2013 Jan 08; 185(1):60. View Five things to know about...celiac disease. Abstract

  70. The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk. Oncogene. 2012 Feb 16; 31(7):884-96. View The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk. Abstract

  71. Long-term management of patients with celiac disease: current practices of gastroenterologists in Canada. Can J Gastroenterol. 2010 Aug; 24(8):499-509. View Long-term management of patients with celiac disease: current practices of gastroenterologists in Canada. Abstract

  72. Long-term follow-up of individuals with celiac disease: an evaluation of current practice guidelines. Can J Gastroenterol. 2007 Sep; 21(9):557-64. View Long-term follow-up of individuals with celiac disease: an evaluation of current practice guidelines. Abstract

  73. On the structure of the stator of the mitochondrial ATP synthase. EMBO J. 2006 Jun 21; 25(12):2911-8. View On the structure of the stator of the mitochondrial ATP synthase. Abstract

  74. The expression, purification, crystallization and preliminary X-ray analysis of a subcomplex of the peripheral stalk of ATP synthase from bovine mitochondria. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jun 01; 62(Pt 6):530-3. View The expression, purification, crystallization and preliminary X-ray analysis of a subcomplex of the peripheral stalk of ATP synthase from bovine mitochondria. Abstract

  75. Solution structure of subunit F(6) from the peripheral stalk region of ATP synthase from bovine heart mitochondria. J Mol Biol. 2004 Sep 10; 342(2):593-603. View Solution structure of subunit F(6) from the peripheral stalk region of ATP synthase from bovine heart mitochondria. Abstract

  76. An inhibitor of poly (ADP-ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart. Br J Pharmacol. 1999 Jul; 127(6):1518-24. View An inhibitor of poly (ADP-ribose) synthetase activity reduces contractile dysfunction and preserves high energy phosphate levels during reperfusion of the ischaemic rat heart. Abstract

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