Catherine L. Salussolia | Medical Services
Specialties
Programs & Services
- Brain Development and Genetics Clinic
- Epilepsy Center
- Epilepsy Genetics Program
- Neurology
- Neuroscience Center
- Tuberous Sclerosis Program
Languages
- English
Catherine L. Salussolia | Education
Undergraduate School
Swarthmore College
2004, Swarthmore, PA
Graduate School
Stony Brook University
2012, Stony Brook, NY
Medical School
Stony Brook University
2014, Stony Brook, NY
Internship
Pediatrics
Stony Brook University
2015, Stony Brook, NY
Residency
Boston Children's Hospital
2019, Boston, MA
Fellowship
Clinical Neurophysiology and Epilepsy
Boston Children's Hospital
Catherine L. Salussolia | Certifications
- American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
Catherine L. Salussolia | Professional History
Dr. Salussolia is a neurologist and epileptologist at Boston Children’s Hospital with board certification in neurology and special qualification in child neurology. She has fellowship training in epilepsy and clinical neurophysiology, as well as in neurogenetics, with a focus on epilepsy genetics and tuberous sclerosis. She is an attending physician in the Epilepsy Genetics Program and the Tuberous Sclerosis Clinic, through which she sees patients for consultations and management of epilepsy.
Dr. Salussolia obtained her Bachelor of Arts in Psychology with a minor in Biology from Swarthmore College. She completed a Masters in Science at Albany Medical College in the Neuropharmacology and Neuroscience, and then received her MD/PhD degrees through the MSTP program at Stony Brook University. Her doctoral work utilized molecular techniques to identify and characterize the biogenesis of ionotropic glutamate receptors (NMDA and AMPA receptors) and its effects on disease states. She completed her pediatrics training at Stony Brook University followed by child neurology residency and fellowship training in clinical neurophysiology and neurogenetics at Boston Children’s Hospital. Her current research focuses on the molecular mechanisms of inhibitory signaling, specifically parvalbumin interneurons, in tuberous sclerosis-associated epilepsy.
Catherine L. Salussolia | Publications
AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. bioRxiv. 2024 Sep 23. View AKT-mediated phosphorylation of TSC2 controls stimulus- and tissue-specific mTORC1 signaling and organ growth. Abstract
Timing the clinical onset of epileptic spasms in infantile epileptic spasms syndrome: A tertiary health center's experience. Epilepsia. 2024 Apr; 65(4):984-994. View Timing the clinical onset of epileptic spasms in infantile epileptic spasms syndrome: A tertiary health center's experience. Abstract
Treatment-Resistant Epilepsy and Tuberous Sclerosis Complex: Treatment, Maintenance, and Future Directions. Neuropsychiatr Dis Treat. 2023; 19:733-748. View Treatment-Resistant Epilepsy and Tuberous Sclerosis Complex: Treatment, Maintenance, and Future Directions. Abstract
Translating Ribosome Affinity Purification (TRAP) of Cell Type-specific mRNA from Mouse Brain Lysates. Bio Protoc. 2022 May 05; 12(9):e4407. View Translating Ribosome Affinity Purification (TRAP) of Cell Type-specific mRNA from Mouse Brain Lysates. Abstract
Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts. Elife. 2021 07 14; 10. View Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts. Abstract
Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia. Brain. 2020 10 01; 143(10):2929-2944. View Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia. Abstract
A Stroke Alert Protocol Decreases the Time to Diagnosis of Brain Attack Symptoms in a Pediatric Emergency Department. J Pediatr. 2020 01; 216:136-141.e6. View A Stroke Alert Protocol Decreases the Time to Diagnosis of Brain Attack Symptoms in a Pediatric Emergency Department. Abstract
Stroke After Cardiac Catheterization in Children. Pediatr Neurol. 2019 11; 100:42-48. View Stroke After Cardiac Catheterization in Children. Abstract
Genetic Etiologies, Diagnosis, and Treatment of Tuberous Sclerosis Complex. Annu Rev Genomics Hum Genet. 2019 08 31; 20:217-240. View Genetic Etiologies, Diagnosis, and Treatment of Tuberous Sclerosis Complex. Abstract
Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors. J Gen Physiol. 2017 Jun 05; 149(6):661-680. View Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors. Abstract
Assembly of AMPA receptors: mechanisms and regulation. J Physiol. 2015 Jan 01; 593(1):39-48. View Assembly of AMPA receptors: mechanisms and regulation. Abstract
Assembly of AMPA receptors: mechanisms and regulation. J Physiol. 2014 Jul 11. View Assembly of AMPA receptors: mechanisms and regulation. Abstract
Asynchronous movements prior to pore opening in NMDA receptors. J Neurosci. 2013 Jul 17; 33(29):12052-66. View Asynchronous movements prior to pore opening in NMDA receptors. Abstract
A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors. J Neurosci. 2013 Jun 05; 33(23):9840-5. View A eukaryotic specific transmembrane segment is required for tetramerization in AMPA receptors. Abstract
Flip-flopping to the membrane. Neuron. 2012 Nov 08; 76(3):463-5. View Flip-flopping to the membrane. Abstract
Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. J Biol Chem. 2011 Nov 18; 286(46):40205-18. View Interaction of the M4 segment with other transmembrane segments is required for surface expression of mammalian a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. Abstract
Arrangement of subunits in functional NMDA receptors. J Neurosci. 2011 Aug 03; 31(31):11295-304. View Arrangement of subunits in functional NMDA receptors. Abstract
Improgan-induced hypothermia: a role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature. Brain Res. 2007 Jun 04; 1152:42-8. View Improgan-induced hypothermia: a role for cannabinoid receptors in improgan-induced changes in nociceptive threshold and body temperature. Abstract