Ji Miao

The ultimate goals of Ji Miao’s research are to understand the development of human diseases associated with dysregulated lipid, cholesterol, glucose, and bile acid metabolism, thus enabling the discovery of targets and treatments for these diseases, particularly diabetes, non-alcoholic fatty liver disease, and cardiovascular diseases.

Specific aims in Miao’s laboratory studies include understanding how insulin regulates nuclear receptors and how the activity of these nuclear receptors is altered in the insulin resistant state, as well as understanding the molecular mechanisms underlying the beneficial effects of bariatric surgery on metabolic regulation.