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Where the bench meets the bedside One in 10 Americans, or more than 30 million people, live with a rare disease. Worldwide it is estimated that more than 350 million people are affected. A condition is considered rare when fewer than 200,000 individuals …
The Chinnapen Lab focuses on both the development of novel technologies to deliver biologics drugs across cellular membrane barriers, and to better understand the cellular mechanisms that underpin this transcellular transport. There are two major …
The Daley Laboratory focuses on stem cell biology, with an emphasis on hematopoietic differentiation from human and mouse embryonic stem cells (ES cells), cellular reprogramming, germ cell development, human disease modeling, and the study of the …
The Engle Lab is a Howard Hughes Medical Institute (HHMI) molecular genetics and developmental neuroscience research lab at Boston Children’s Hospital and affiliated with Harvard Medical School and the Broad Institute . The lab’s primary mission is …
The Geha Laboratory aims to understand how perturbations in the immune system result in human disease. We have two main foci of investigation: Mechanisms underlying primary immunodeficiencies. Primary immunodeficiencies (PIDs) constitute an …
The Ingber Laboratory is interested in the general mechanism of cell and developmental regulation: how cells respond to signals and coordinate their behaviors to produce tissues with specialized form and function. The specific focus is on control of …
Our immune system faces the challenge of defending us from colonization by microbes that surround us every day. Some of these microbes are beneficial, and can help us obtain nutrients from the environment. Others are predatory, and can cause …
The Klagsbrun Laboratory is focused on the study of growth factors and their receptors, in particular, those that regulate the development of blood vessels, a process known as angiogenesis. Team Section Header Principal Investigator Team Members 164688 …
Welcome to the Kunkel Laboratory! Division of Genetics and Genomics at Boston Children's Hospital The primary focus of the Kunkel laboratory is the study of muscle diseases, including Duchenne Muscular Dystrophy (DMD), a progressive muscle wasting disease …
We are committed to understanding the fundamental mechanisms that regulate the development and life-long health of the mammalian brain. The brain is bathed by cerebrospinal fluid (CSF), which fills the brain’s ventricles or cavities. In the developing …