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Welcome to the Loddenkemper Lab Our mission is to prevent, predict, detect, and treat every seizure and status epilepticus in children before it occurs. We envision a world in which seizure freedom is achieved for all children through closed-loop early …
Download the paper: Whole-Exome Sequencing Enables a Precision Medicine Approach for Kidney Transplant Recipients, Nina Mann et al., JASN Feb 2019, 30 (2) 201-215 The identification of monogenic mutations in one of the following genes may have …
The Priebe Laboratory, located in the Enders Research Building of Boston Children's Hospital, studies the bacterial pathogens Pseudomonas aeruginosa and the Burkholderia cepacia complex, with the long-term goal of developing vaccines and new …
The Rossi Laboratory has a profound interest in understanding the mechanisms enabling self-renewal and multi-potency in HSCs, which we study using cellular, molecular, genetic and epigenetic approaches. Another focus of the lab is in understanding the …
The Sankaran Laboratory uses human genetics to study hematopoiesis and how this process goes awry in human disease. Learn more by visiting www.bloodgenes.org . sankaran-laboratory-research Sankaran Laboratory Sankaran Laboratory Sankaran Laboratory The …
The Zanoni lab seeks to understand the events that initiate protective immunity in response to infection and tissue injury, or that drive the development of immune-mediated diseases; to this end, we scrutinize innate immune cell biology, with a primary …
The Yuki Laboratory studies the pathophysiology of organ injury driven by myeloid cells in sepsis and surgical induced systemic inflammation. In addition, we have been studying the role of anesthetics in perioperative immune function and their outcomes. …
Epigenetic modifications, particularly DNA methylation and covalent histone modifications, play an important role in regulating chromatin dynamics and therefore have a significant impact on gene expression. The Zhang Lab has been interested in: (1) how …
Transcriptional regulation in normal and malignant hematopoiesis The broad interests of the Cantor Laboratory are to elucidate the gene regulatory mechanisms involved in normal blood cell development and to understand how their dysregulation leads to …
The Remold-O’Donnell Laboratory studies the role of SerpinB1 in protecting the host defenses of the lung against microbial infection. SerpinB1 (also called MNEI) is an ancestral and highly conserved serine protease inhibitor and a highly efficient …