Summary
Newborns with congenital heart disease (CHD) are at increased risk of developing postpartum and postoperative blood clots after cardiac surgery. The molecular mechanisms that are responsible for the clotting profile predisposing children to blood clots in the early stages of life are currently not well described. The goal of this proposal is to prospectively collect plasma samples from ten (10) neonates with antenatal diagnosis of severe congenital heart disease (CHD) to better understand mechanisms responsible for abnormal clotting in the perioperative period.
Conditions
Congenital Heart Disease, Single-ventricle, Thrombosis
Recruitment Status
NOT_YET_RECRUITING
Eligibility Criteria
Inclusion Criteria:
* All neonates with a diagnosis of severe Congenital Heart Disease undergoing surgery at Boston Children's Hospital in the first week of life
Exclusion Criteria:
* None
Intervention
Intervention Type
Intervention Name
OTHER
Collecting discarded blood samples
Gender
ALL
Min Age
1 Day
Max Age
7 Days
Download Date
2024-05-30
Principal Investigator
N/A
Primary Contact Information
rachel.bernier@childrens.harvard.edu
Hanna Van Pelt, BS
hanna.vanpelt@childrens.harvard.edu
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Contact
For more information and to contact the study team: