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Critical Care Infection Prevention Program (CCIPP)

The Critical Care Infection Prevention Program (CCIPP) consists of the Nosocomial Infection Oversight Committee (NIOC), and the Translational Research for Infection Prevention in Pediatric Anesthesia and Critical Care (TRIPPACC) Program.  

microscopic image of a covid-19 cell.

Nosocomial Infection Oversight Committee (NIOC) 

NIOC is a hospital-level committee that focuses on hospital-acquired infection surveillance and prevention in the hospital’s four Intensive Care Units (ICUs) and the oncology/stem cell transplant programs. NIOC’s multidisciplinary membership includes the Infection Prevention and Control Department, unit-based infection prevention nurses, and ICU nursing and physician leaders. NIOC continually optimizes infection prevention bundles, including those targeting ventilator-associated pneumonia (VAP) and ventilator-associated events (VAE), central-line associated bloodstream infections (CLABSI), surgical site infections (SSI), and catheter-associated UTI (CAUTI). In 2019, BCH saw a >50% drop in the CLABSI rate (centerline) based in large part on NIOC efforts. This was the first drop in the CLABSI centerline in more than 10 years. 

Translational Research for Infection Prevention in Pediatric Anesthesia and Critical Care (TRIPPACC) 

TRIPPACC is a collaborative research group of physician scientists and basic scientists, including investigators in pediatric critical care medicine, microbial pathogenesis and genomics, infection prevention and control, epidemiology, clinical microbiology, and systems biology.  

The guiding principle of the TRIPPACC Program is that microbial whole-genome sequencing can reveal transmission patterns as well as mechanisms of pathogenicity and antibiotic resistance, which can lead to novel targets for therapeutics and vaccines.  

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