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Research Team

Ke Yuan Lab Team Spring 2022

Current Members

Ke Yuan Headshot

Ke Yuan, PhD FAHA

Assistant Professor
2017 Class of Parker B Francis Fellow
ke.yuan@childrens.harvard.edu

Ke received her PhD in Biology from Temple University, PA, and was then a postdoctoral fellow at the Division of Pulmonary Critical Care Medicine at Stanford University when she joined the faculty. Ke has been recognized nationally as a Parker B Francis Fellow, a fellow of American Heart Association (AHA) and a recipient of AHA Scientist Development Grant, Cournand and Comroe Young Investigator Award. 

I enjoy reading, painting, jogging and watching TV shows. My fav movies are Harry Potter, The Lord of the Rings, Star Wars & Star Trek. I wish I could be the one with Force and the Force is always with me.

Tim Klouda Headshot

Tim Klouda, DO

Clinical Fellow
NHLBI T32 Awardee
Timothy.klouda@childrens.harvard.edu

After attending medical school at the University Of New England College Of Osteopathic Medicine in Biddeford, ME  I moved to Philadelphia, PA to complete a pediatric residency at St. Christopher’s Hospital for Children. There I decided to pursue a career in pediatric pulmonology and started fellowship at Boston Children’s Hospital in July 2019. I joined Ke Yuan’s lab in September 2020 with an interest in studying pericyte’s role in the development pulmonary hypertension induced by sheer stress.  Our research uses the murine pneumonectomy model and investigates not only pericytes but the contribution of other vascular cells in the development of pulmonary hypertension. My other clinical and research interests include lung transplantation and the vascular malformations.  In my spare time I enjoy trying new restaurants in the city and spending time with my fiancée Amy and puppy Penelope.

Hyunbum Kim Headshot

Hyunbum Kim, PhD

Postdocteral Fellow
Hyunbum.kim@childrens.harvard.edu

Hyunbum received B.S. from Department of Biotechnology, Yonsei University and M.S./Ph.D. degrees from Department of Chemical and Biological Engineering, Seoul National University, South Korea. His PhD thesis focused on the development of effective stem cell therapy by cell surface modification. As a postdoctoral fellow in Dr. Ke Yuan lab, he has been working on pulmonary circulation research included 1) Pericyte lineage tracing in severe pulmonary hypertension related with hypoxia-inducible factor 2-alpha signaling pathway 2) RNA-editing in smooth muscle cells that contributes to immune responses during the pulmonary vascular remodeling. In his spare time, Hyunbum enjoys jogging along the Charles River, playing tennis and watching movies.

Jiwon Kim Headshot

Jiwon Kim, BS

Research Assistant
Jiwon.kim@childrens.harvard.edu

Jiwon is currently working full time as research assistant in the Ke Yuan Lab. She graduated from Washington and Lee University in 2020 with a BS in Neuroscience and a minor in Music. Her main responsibilities include maintaining mouse house, managing administrative duties, and supporting and conducting experiments. Jiwon’s main project is to determine the role of pericytes in the early onset of CTD-PAH development in mice. Outside of the lab, Jiwon enjoys sunbathing, hiking, and spending time in a library/bookstore.

Tiffany Liu Headshot

Tiffany Liu, BS

Research Assistant
Tiffany.Liu@childrens.harvard.edu

Tiffany received her B.S. in Medical and Molecular Biology with a minor in Health Psychology from MCPHS University along with a minor in Performing Arts from the Colleges of the Fenway in 2021. She is currently a full time research assistant in the Ke Yuan Lab. Her main project involves studying the intersection between lymphatics and pulmonary arterial hypertension. In her spare time, she likes to attend musicals in the Boston area, read fiction books, and play video games.

Alumni

Testimonial of work with Dr. Ke Yuan

"Working with Dr. Yuan was an exceptional learning experience. It was a mixture of proper guidance and autonomy so that I could properly execute our projects. From the very beginning, I was made part of a team and it made me quickly comfortable in the lab. Prior to entering medical school, she acted as a mentor, giving me advice and helping me, especially with my interviewing skills. To this day, I still feel very comfortable reaching out to Dr. Yuan for help. I look back at my time working with her very fondly."

Marielle Discipulo, MD,