Search Results
Lysosomal Storage Disorders *present and past members of the laboratory are bolded Rohanizadegan M, Abdo SM, O’Donnell-Luria A, Mihalek I , Chen P, Sanders M, Leeman K, Cho M, Hung C , Bodamer O . Utility of rapid whole-exome sequencing in the diagnosis …
Name Title E-mail Address Douglas Cowan Associate Professor douglas.cowan@childrens.harvard.edu Jerusha Thedsanamoorthy Research Assistant thedsanamoorthy.j@husky.neu.edu Rouan Yao Research Assistant rouan.yao@childrens.harvard.edu Collaborators Name …
cover-art Cowan Lab | Cover Art … Cover Art …
Hematopoietic development: ESC/iPSC are pluripotent stem cells, yet mechanisms of directed differentiation into HSC and models for functional engraftment remain poorly defined. We study hematopoietic development in mouse embryos and we differentiate mouse …
Tumor cells attract blood vessels needed to deliver oxygen and nutrients, a prerequisite for tumor growth. Dr. Folkman suggested that cancer is an angiogenesis-dependent process. tumor-angiogenesis Tumor Angiogenesis … Tumor …
Questions? We want to hear from you! We would be happy to discuss aspects of our research with you in greater detail. If you or a member of your family is affected by one of the disorders that we are studying and you have questions or comments, please …
Lee J, Salazar Hernández MA, Auen T, Mucka P, Lee J, Ozcan U. PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolism. Molecular Metabolism, 2017 Oct 28. pii: S2212-8778(17)30737-8 [ Pubmed ] Sharabi K, Lin H, Tavares CD, Dominy JE, …
Chemical Chaperones Our final investigation area is developing more potent chemical chaperones to treat insulin and leptin resistance and consequently type 2 diabetes and obesity, respectively. We have made important progress in this area and already …
2022 Dec We have had an exciting year with many accomplishments to celebrate! We welcomed two new postdocs: Sivan Gelb and Alexandra Hochstetler and one new graduate student Jill Jones! We also enjoyed hosting summer students Arianna Bethea from Bunker …
In the media Beyond Fitbit: The quest to develop medical-grade wearables ( Reuters, Fox News 12/18/15) From wearables to robotics: Boston Children's Hospital shows off health innovations ( Boston Business Journal, 4/7/15 ) Boston Children’s Hospital …