Multisystem inflammatory syndrome in children (MIS-C) is a potentially life-threatening complication of coronavirus disease (COVID-19). While the typical symptoms of MIS-C include severe inflammation, heart problems, and blood clotting, some children with MIS-C have neurological symptoms such as visual hallucinations, confusion, or headache. It is not yet known whether children with MIS-C make a full neurological recovery, or if there are lasting consequences such as learning problems, mental health challenges (e.g., anxiety), or difficulties in carrying out daily activities.
We are conducting a study of the long-term impacts of MIS-C on children's brain development and cognitive functioning. The purpose of this study is to describe the neurological outcomes of children with MIS-C over time. In particular, we will focus on cognitive skills (e.g., problem solving, organization), activities of daily living (e.g., getting dressed, brushing teeth), and quality of life. We will also try to understand what makes children more likely to have a good or poor neurological outcome after MIS-C. Some of our research may lead to new ways of caring for children affected by MIS-C.
Study Contact Information

Julia Rohde, Clinical Research Coordinator
NeuroMISC@childrens.harvard.edu
617-355-8525