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Current Research Projects | Overview

 

  • Influence of IgE on mast cell homeostasis in the intestine
  • The function of food-specific IgG antibodies and signaling, via FcyRIIb, on inhibition both in immediate hypersensitivity reactions mediated by mast cells and basophils as well as on APC:T cell          interactions in the intestine and the emerging Th2/Treg balance
  • FcyRIIb signaling pathways in mast cells
  • Cell intrinsic differences in basophil sensitivity to allergens as a basis of the widely variable sensitivity of patients with food allergen-specific IgE to food ingestion