The PKlab at Boston Children’s Hospital (BCH) was formally created to provide clinicians and researchers with a core competence in Quantitative Clinical Pharmacology and Pharmacometrics (QCPP). - “Pharmacometrics is the science which deals with …

  The Yu laboratory conducts genome-wide and world-wide analyses of genetic determinants of autism to reveal its underlying genomic architecture, and neurobiological underpinnings. Current Projects Translational Pediatric Genomic Medicine We are …

Discover, define, disrupt Discovering pathways of RNA regulation for the development of new therapies for cancer and other diseases.     Knowledge to cure Our research is focused on identifying and characterizing new mechanisms of RNA regulation in the …

  Research in the lab aims to understand how cells sense and interacts with their surroundings and how membrane channels and transporters contribute to immune function, host-microbial symbiosis, and cellular metabolism. Research projects in the lab use a …

  The Pellman Laboratory uses a combination of genetics, biochemistry and live-cell imaging to study cell division and the maintenance of genome stability. Projects are aimed at defining the molecular mechanisms underlying polarized morphogenesis and …

The Retina and Vascular Development Our lab investigates factors regulating the vascular development of the retina using several in vivo models. We are dedicated to developing ways to improve therapies for vascular eye diseases, such as retinopathy of …

The Agrawal Laboratory research is focused on determining the genetic and molecular basis of congenital myopathies and various orphan diseases. With the advent of technologies such as whole exome and genome sequencing, we are able to identify novel genes …

  Immunologists in the Winau Lab are most excited about the discovery of basic mechanisms that explain how the immune system functions. Over the years, we added to the passion for basic science a strong interest in identifying targets for possible …

  The Image, Informatics and Intelligence (i3) Lab aims to improve healthcare by imaging informatics. Our work is at the intersection of:  medical image analysis machine/deep learning and artificial intelligence (AI) big data and data science …

  The Rogers laboratory works to develop new therapies for endometriosis, cancer, and blinding eye disease. To achieve these goals we use mouse models of disease, mouse genetic approaches, high-throughput screening, CRISPR genome editing, as well as …