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  Allergic Diseases Galand, C., Leyva-Castillo, J.M., Yoon, J., Han, A., Lee, M.S., McKenzie, A., Stassen, M., Oyoshi, M.K. and Geha, R.S. IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells. J. All.Clin. Immunol. In …

  Judah Folkman (1933-2008) pioneered the field of angiogenesis and its role in pathology, such as in cancer. Angiogenesis is a complex process of many steps. The zebrafish is a good model for analyzing the molecular basis of vasculogenesis and …

  A major goal in angiogenesis research has been to inhibit tumor angiogenesis and growth. One approach has been to block NRP expression. Both mouse knockouts and zebrafish knockdowns show that angiogenesis is NRP-dependent. NRP knockdown in zebrafish …

Our research goals The common fundamental goals of the projects are to characterize and understand normal and abnormal patterns of gene expression in developing muscle from the stem cell state through to maturity. Further, we aim to understand the …

  More information about all clinical trials can be found at: clinicaltrials.gov More information about Interstitial Cystitis can be found at: Interstitial Cystitis Network More information about Neuromuscular Disorders can be found at: Muscular Dystrophy …

1) Obtain written informed consent 2) Locate specimens To participate we will need: Blood samples from the affected participants and all available and consenting first-degree relatives. Unfixed, frozen muscle tissue,  for the Neuromuscular Disorder …

  We have an open position for a Research Assistant to join our lab. The ideal candidate has experience working with mouse models and demonstrated ability with molecular and cell biology techniques. This is a great opportunity for a recent college …

Leptin Signaling Leptin is an adipocyte-derived hormone that suppresses appetite mainly through its action on a subset of hypothalamic neurons. It also allows the body to expend energy necessary for growth, reproduction, and immunity. The discovery of …

Learn about our current research projects: Intelligible Predictive Health Models Fair Machine Learning for Health Care Automating Digital Health Intelligible Predictive Health Models We study both black-box and glass-box ML methods to improve the …