Current Environment: Production

Principal Investigator

Charles B. Berde, MD, PhD

Charles Berde, MD, PhD

Sara Page Mayo Chair, Pediatric Pain Medicine

Professor of Anaesthesia (Pediatrics), Harvard Medical School

Dr. Berde is the Sara Page Mayo Chair in Pediatric Pain Medicine and Professor of Anaesthesia (Pediatrics) at Harvard Medical School. He completed an MD and PhD (Biophysics) at Stanford University; his Residency in Pediatrics, at Boston Children's Hospital; Residency in Anesthesiology, at Massachusetts General Hospital; and Fellowship in Pediatric Anesthesiology, at Boston Children's Hospital.

Dr. Berde co-founded the Pain Treatment Center at Boston Children's Hospital, the first and most clinically active acute and chronic pain management program for children in the world. Dr. Berde’s translational research concerns local anesthetic mechanisms and the development of novel prolonged duration local anesthetics that are now in clinical trials. His clinical research concerns clinical pharmacology of analgesics and local anesthetics in children, clinical outcomes of treatment of neuropathic pain and cancer pain in children, functional brain imaging of children with neuropathic pain, and brain dynamic studies in children during general anesthesia. Translation research on novel prolonged duration local anesthetics has progressed for our laboratory to clinical trials.

Dr. Berde is the author of over 130 original peer-reviewed articles and over 100 chapters and reviews. He was profiled as one of Time Magazine's "Heroes in Medicine" in 1997. He has received several awards and honors for his pioneering work in pediatric pain relief, including the 2003 Scientific Achievement Award of the Reflex Sympathetic Dystrophy Syndrome Association, the 2015 IASP Special Interest Group in Pediatric Pain Distinguished Career Award, the 2018 Myron Yaster Lifetime Achievement Award from the Society for Pediatric Anesthesia, and the 2018 John J. Bonica Award from the American Society of Regional Anesthesia and Pain Medicine.

Instructors

Laura Cornelissen, PhD

Laura Cornelissen, PhD [Email] [Publications] [ResearchGate]

Dr. Cornelissen received her PhD in Neuroscience from University College London, UK. Her research interests are in the neurophysiology of acute and chronic pain, analgesia and general anesthesia in infants, children, and adolescents.

 

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Joe Kossowsky, PhD [Email] [Publications] [ResearchGate]

Dr. Kossowsky received his PhD in Clinical Psychology and Neuroscience from University of Basel, Switzerland. His current research is focused on post-operative pain, placebo effects, and clinical trials design. Dr. Kossowsky completed his psychotherapy training and worked as a psychotherapist with children and adolescents at the psychotherapeutic outpatient clinic at the University of Basel.

Research Fellows

Carolina Donado, MD

Carolina Donado, MD [Email] [Publications]

Dr. Donado earned her medical degree at Universidad de los Andes in Bogotá, Colombia in 2011. Her main focus in pain research has been in outcome measures involving acute and chronic pain management. Her main interest is in pediatric care and pain management.

 

Suratsawadee Wangnamthip, MD

Suratsawadee Wangnamthip, MD

Dr. Jenna Suratsawadee Wangnamthip is an Anesthesiologist, Pain Specialist and Lecturer at the Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand. Her works include chronic pain, cancer pain management, pain intervention, and acute pain management. Her research interests are in pediatric cancer pain and neuropathic pain.

Biostatistician

Kimberly Lobo, MS, MPH

Kimberly Lobo, MS, MPH [Email] [Publications] [ResearchGate]

Kimberly Lobo earned her Master in Public Health degree in Epidemiology from Boston University. She also has a Master of Science degree in Biochemistry from University of Mumbai, India. Her research interests include the application of epidemiologic and statistical methods for clinical trials and outcomes research, study design, survey methodology, health disparities, and longitudinal data analysis.

Clinical Fellow

Omri David Soffer, MD

Omri David Soffer, MD

David Soffer received his MD degree from Semmelweis Egyetem/Semmelweis University and is a second-year Neonatology Fellow at Boston Children's Hospital. Dr. Soffer is currently developing a clinical protocol to assess the depth of neuromuscular blockade in neonates. He is also interested in medical ethics and neonatal pain management.

 

Resident Physician

Luai Zakaria, MD

Luai Zakaria, MD

Luai Zakaria received his MD degree from The University of Chicago and is a Resident Physician at Brigham and Women's Hospital. Dr. Zakaria is using advanced signal processing to analyze cortical dynamics during general anesthesia. He is specifically looking at age-dependent phase-amplitude coupling during maintenance anesthesia and emergence from anesthesia.

 

Students

Angela Kim

Angela Kim

Angela is an undergraduate student at Harvard College (class of 2021). Angela is applying computational and quantitative methods to analyze biological signals in patients under general anesthesia or drug-induced muscle paralysis.

Resident Physician

Luai Zakaria, MD

Luai Zakaria, MD

Luai Zakaria received his MD degree from The University of Chicago and is a Resident Physician at Brigham and Women's Hospital. Dr. Zakaria is using advanced signal processing to analyze cortical dynamics during general anesthesia. He is specifically looking at age-dependent phase-amplitude coupling during maintenance anesthesia and emergence from anesthesia.

Students

Angela Kim

Angela Kim

Angela is an undergraduate student at Harvard College (class of 2021). Angela is applying computational and quantitative methods to analyze biological signals in patients under general anesthesia or drug-induced muscle paralysis.